Title:
OPTICAL SENSOR WITH ENHANCED SENSITIVITY
Document Type and Number:
WIPO Patent Application WO/2012/111001
Kind Code:
A3
Abstract:
The invention is a surface plasmon resonance (SPR) sensor to determine the presence and quantity of biological or chemical entities in an analyte. The sensor comprises a metal periodic structure deposited as a thin layer of a noble metal, comprising a one dimensional array of nanoslits or a two dimensional array of nanoholes on a transparent dielectric substrate, a nm-thick layer of transparent dielectric protection layer on top of the metal periodic structure and a functionalization layer, which acts as a binding layer to biological or biochemical entities in an analyte that is in contact with the functionalization layer. The sensor of the invention has the following properties: the spaces perforated in the metal are at least partially filled by a material with a refractive index as dose as possible to that of the substrate; the thickness of the metal layer is no more than 10Onm.
Inventors:
ABDULHALIM IBRAHIM (IL)
Application Number:
PCT/IL2012/000075
Publication Date:
November 01, 2012
Filing Date:
February 14, 2012
Export Citation:
Assignee:
UNIV BEN GURION (IL)
ABDULHALIM IBRAHIM (IL)
ABDULHALIM IBRAHIM (IL)
International Classes:
G01N21/00
Foreign References:
| US20080280374A1 | 2008-11-13 | |||
| US20090236614A1 | 2009-09-24 | |||
| US20110301066A1 | 2011-12-08 |
Other References:
KARABCHEVSKY, A ET AL.: "Theoretical and Experimental Investigation of Enhanced Transmission Through Periodic Metal Nanoslits for Sensing in Water Environment.", PLASMONICS, vol. 4, 18 September 2009 (2009-09-18), pages 281 - 292
Attorney, Agent or Firm:
LUZZATTO & LUZZATTO et al. (Beer Sheva, IL)
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