Title:
OPTICALLY ACTIVE TRANS-ASTAXANTHIN DERIVATIVE OR SALT THEREOF, AND COMPOSITION CONTAINING SAID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2019/103139
Kind Code:
A1
Abstract:
Provided are: an optically active trans-astaxanthin derivative or a salt thereof, which has excellent antioxidative activity, while having excellent water solubility and the like; and a composition which contains this derivative or a salt thereof with high purity. An optically active trans-astaxanthin derivative represented by formula (I) or a salt thereof. (In the formula, m1, m2, n1 and n2 may be the same as or different from each other, and each represents an integer of 1-6.)
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Inventors:
FUJITA TAKASHI (JP)
KOBAYASHI SATOSHI (JP)
SHINOHARA RYOMA (JP)
IWANO YUJI (JP)
MORIIZUMI KIYOTAKA (JP)
MAEDA SACHI (JP)
SAKATA RYO (JP)
NISHIDA YASUHIRO (JP)
TAKASHINA MICHINORI (JP)
YOKOYAMA TOMIHISA (JP)
KOBAYASHI SATOSHI (JP)
SHINOHARA RYOMA (JP)
IWANO YUJI (JP)
MORIIZUMI KIYOTAKA (JP)
MAEDA SACHI (JP)
SAKATA RYO (JP)
NISHIDA YASUHIRO (JP)
TAKASHINA MICHINORI (JP)
YOKOYAMA TOMIHISA (JP)
Application Number:
PCT/JP2018/043376
Publication Date:
May 31, 2019
Filing Date:
November 26, 2018
Export Citation:
Assignee:
ASTA PHARMACEUTICALS CO LTD (JP)
International Classes:
C07C403/24; A61K31/22; A61P39/06
Domestic Patent References:
| WO2015178404A1 | 2015-11-26 |
Foreign References:
| JP2018131390A | 2018-08-23 |
Other References:
EDITION OF THE CHEMICAL SOCIETY OF JAPAN , KIKAN KAGAKU SOSETSU NO.6 SEPARATION OF OPTICAL ISOMERS, vol. 124, 1999, Tokyo, pages 8 - 9, ISBN: 4-7622-3600-4
JACKSON, H. L. ET AL.: "Synthesis, characterization, and direct aqueous superoxide anion scavenging of a highly water-dispersible astaxanthin-amino acid conjugate", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 15, 2 August 2004 (2004-08-02), pages 3985 - 3991, XP055617465, ISSN: 0960-894X
JACKSON, H. L. ET AL.: "Synthesis, characterization, and direct aqueous superoxide anion scavenging of a highly water-dispersible astaxanthin-amino acid conjugate", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 15, 2 August 2004 (2004-08-02), pages 3985 - 3991, XP055617465, ISSN: 0960-894X
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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