Title:
OPTIMIZED CELLULASE ENZYMES
Document Type and Number:
WIPO Patent Application WO/2011/098551
Kind Code:
A3
Abstract:
The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.
Inventors:
KETTLING ULRICH (DE)
REISINGER CHRISTOPH (DE)
BRUECK THOMAS (DE)
KOLTERMANN ANDRE (DE)
GERLACH JOCHEN (DE)
UNTERSTRASSER ISABEL (DE)
ROECHER LUTZ (DE)
RARBACH MARKUS (DE)
CLAREN JOERG (DE)
KOHL ANDREAS (DE)
PIECK JAN CARSTEN (DE)
SCHLOSSER DOMINIK (DE)
REISINGER CHRISTOPH (DE)
BRUECK THOMAS (DE)
KOLTERMANN ANDRE (DE)
GERLACH JOCHEN (DE)
UNTERSTRASSER ISABEL (DE)
ROECHER LUTZ (DE)
RARBACH MARKUS (DE)
CLAREN JOERG (DE)
KOHL ANDREAS (DE)
PIECK JAN CARSTEN (DE)
SCHLOSSER DOMINIK (DE)
Application Number:
PCT/EP2011/052023
Publication Date:
May 31, 2012
Filing Date:
February 11, 2011
Export Citation:
Assignee:
SUED CHEMIE AG (DE)
KETTLING ULRICH (DE)
REISINGER CHRISTOPH (DE)
BRUECK THOMAS (DE)
KOLTERMANN ANDRE (DE)
GERLACH JOCHEN (DE)
UNTERSTRASSER ISABEL (DE)
ROECHER LUTZ (DE)
RARBACH MARKUS (DE)
CLAREN JOERG (DE)
KOHL ANDREAS (DE)
PIECK JAN CARSTEN (DE)
SCHLOSSER DOMINIK (DE)
KETTLING ULRICH (DE)
REISINGER CHRISTOPH (DE)
BRUECK THOMAS (DE)
KOLTERMANN ANDRE (DE)
GERLACH JOCHEN (DE)
UNTERSTRASSER ISABEL (DE)
ROECHER LUTZ (DE)
RARBACH MARKUS (DE)
CLAREN JOERG (DE)
KOHL ANDREAS (DE)
PIECK JAN CARSTEN (DE)
SCHLOSSER DOMINIK (DE)
International Classes:
C12N9/42
Domestic Patent References:
| WO2009138877A2 | 2009-11-19 | |||
| WO2009139839A1 | 2009-11-19 | |||
| WO2010005553A1 | 2010-01-14 | |||
| WO2006117432A1 | 2006-11-09 | |||
| WO2009108941A2 | 2009-09-03 | |||
| WO2004016760A2 | 2004-02-26 | |||
| WO2001004284A1 | 2001-01-18 |
Foreign References:
| US20030170861A1 | 2003-09-11 |
Other References:
DATABASE UniProt [online] 1 February 2005 (2005-02-01), "SubName: Full=Cellobiohydrolase;", XP002593511, retrieved from EBI accession no. UNIPROT:Q5MBA7 Database accession no. Q5MBA7
DATABASE PDB [online] 24 February 2009 (2009-02-24), GRASSNICK ET AL.: "3-DIMENSIONAL STRUCTURE OF NATIVE CEL7A FROM TALAROMYCES EMERSONII", XP002593512, retrieved from EBI accession no. PDB:1Q9H Database accession no. 1Q9H
DATABASE PDB [online] 24 February 2009 (2009-02-24), GRASSNICK ET AL.: "3-DIMENSIONAL STRUCTURE OF NATIVE CEL7A FROM TALAROMYCES EMERSONII", XP002593512, retrieved from EBI accession no. PDB:1Q9H Database accession no. 1Q9H
Attorney, Agent or Firm:
SIEGERT, Georg et al. (Arabellastrasse 4, Munich, DE)
Download PDF:
Previous Patent: METHOD AND DEVICE FOR PRODUCING LABELS
Next Patent: METHODS AND COMPOSITIONS FOR THE PREPARATION OF AEROSOLS
Next Patent: METHODS AND COMPOSITIONS FOR THE PREPARATION OF AEROSOLS