Title:
OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY
Document Type and Number:
WIPO Patent Application WO/2019/028281
Kind Code:
A3
Abstract:
The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
Inventors:
NGUYEN QUYEN (US)
WHITNEY MIKE (US)
HINGORANI DINA (US)
TSIEN ROGER (US)
ADAMS STEPHEN (US)
WHITNEY MIKE (US)
HINGORANI DINA (US)
TSIEN ROGER (US)
ADAMS STEPHEN (US)
Application Number:
PCT/US2018/045054
Publication Date:
April 11, 2019
Filing Date:
August 02, 2018
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
NGUYEN QUYEN T (US)
WHITNEY MIKE (US)
HINGORANI DINA (US)
TSIEN ROGER Y (US)
ADAMS STEPHEN (US)
NGUYEN QUYEN T (US)
WHITNEY MIKE (US)
HINGORANI DINA (US)
TSIEN ROGER Y (US)
ADAMS STEPHEN (US)
International Classes:
A61K38/10; A61P25/00; C07K7/08; C07K17/02; G01N33/53; G01N33/68
Foreign References:
| US20120148499A1 | 2012-06-14 | |||
| US20170157208A1 | 2017-06-08 | |||
| US20140010861A1 | 2014-01-09 |
Other References:
DATABASE PROTEIN [online] 23 September 2016 (2016-09-23), ANONYMOUS: "PREDICTED:Uncharacterized Protein LOC108770849 (Trachymyrmex Cornetzi)", XP055590819, retrieved from NCBI Database accession no. XP_018378085
Attorney, Agent or Firm:
MACDOUGALL, Christina, A. et al. (US)
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