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Patent Searching and Data


Title:
OPTINEURIN AND GLAUCOMA
Document Type and Number:
WIPO Patent Application WO2004039312
Kind Code:
A3
Abstract:
Methods of detection, prognosis and diagnosis of the presence or absence of optineurin-associated glaucoma or of an optineurin-associated increased risk of glaucoma are described, in which a sample is tested for the presence of certain sequence alterations in the gene, optineurin, that are associated with glaucoma or with an increased risk of glaucoma, as are methods in which a sample is tested for the presence of alterations in expression of the optineurin polypeptide, as well as methods in which a sample is tested for the presence of alterations in optineurin polypeptide expression or activity. Also described are methods of therapy of glaucoma, utilizing optineurin therapeutic agents.

Inventors:
SARFARAZI MANSOOR
REZAIE TAYEBEH
CHILD ANNE HAWTHORNE
Application Number:
US0320165W
Publication Date:
July 08, 2004
Filing Date:
June 26, 2003
Export Citation:
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Assignee:
UNIVERSITY OF CONNECTICUT
ST. GEORGE'S ENTERPRISES LIMITED
International Classes:
A47G25/10; A47G25/48; B24D3/28; B24D3/34; B24D7/00; C08L61/06; C08L61/14; C09C1/40; C09C3/12; C09K3/14; C12Q1/68; (IPC1-7): C12Q1/68; C07H21/04
Foreign References:
US20010053519A12001-12-20
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