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Title:
ORAL ADMINISTRATION AGENT FOR PREGNANT WOMEN
Document Type and Number:
WIPO Patent Application WO/2022/255284
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an oral administration agent for pregnant women for increasing the concentration of short-chain fatty acids in the blood of a pregnant woman or the fetus, for imparting resistance to obesity to the fetus, or for preventing postnatal obesity or disorders caused by postnatal obesity in the fetus. For achieving this purpose, provided is an oligosaccharide-containing oral administration agent for pregnant women, said oral administration agent for pregnant women being for increasing the concentration of short-chain fatty acids in the blood of a pregnant woman or the fetus, for imparting resistance to obesity to the fetus, or for preventing postnatal obesity or disorders caused by postnatal obesity in the fetus.

Inventors:
KIMURA IKUO (JP)
MIYAMOTO JUNKI (JP)
KOZUTSUMI DAISUKE (JP)
TAKASUGI SATOSHI (JP)
Application Number:
PCT/JP2022/021862
Publication Date:
December 08, 2022
Filing Date:
May 30, 2022
Export Citation:
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Assignee:
THE FOOD SCIENCE INST FOUNDATION (JP)
International Classes:
A23L33/125; A61K31/702; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P15/00
Foreign References:
JP2021017414A2021-02-15
JP2021017414A2021-02-15
Other References:
KIMURA IKUO, MIYAMOTO JUNKI, OHUE-KITANO RYUJI, WATANABE KEITA, YAMADA TAKAHIRO, ONUKI MASAYOSHI, AOKI RYO, ISOBE YOSUKE, KASHIHAR: "Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 367, no. 6481, 28 February 2020 (2020-02-28), US , XP093009937, ISSN: 0036-8075, DOI: 10.1126/science.aaw8429
HARA HIROSHI: "Physiological Effects of Short-Chain Fatty Acid Produced from Prebiotics in the Colon", BIOSCIENCE AND MICROFLORA, JAPAN BIFIDUS FOUNDATION, TOKYO, JP, vol. 21, no. 1, 1 January 2002 (2002-01-01), JP , pages 35 - 42, XP093009939, ISSN: 1342-1441, DOI: 10.12938/bifidus1996.21.35
JUNKI MIYAMOTO ET AL., THE LIPID, vol. 27, no. 2, pages 2016 - 4
"Guidelines for the management of obesity disease in children and adolescents 2017", 14 April 2017, LIFE SCIENCE PUBLISHING CO., LTD.
"Guideline for Early-childhood Obesity", March 2019, JAPAN PEDIATRIC SOCIETY, article "nutrition committee, childhood obesity subcommittee"
KIMURA ET AL., SCIENCE, vol. 367, no. 6481, 2020, pages 8429
MIYAMOTO ET AL., PNAS, vol. 116, no. 47, 2019, pages 23813 - 23821
Attorney, Agent or Firm:
MIYAJIMA Manabu et al. (JP)
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