Title:
ORAL COMPOSITE TABLET COMPRISING EZETIMIBE AND ROSUVASTATIN
Document Type and Number:
WIPO Patent Application WO/2018/101681
Kind Code:
A1
Abstract:
An oral composite tablet and a method of preparing the same are provided. The oral composite tablet includes: an ezetimibe wet granule portion including ezetimibe; and a rosuvastatin mixture portion including rosuvastatin or a pharmaceutically acceptable salt thereof, wherein the ezetimibe wet granule portion includes, as a binder, povidone having a weight average molecular weight of about 30,000 to about 50,000, and the rosuvastatin mixture portion includes a diluents including a water-soluble diluent and a water-insoluble diluent, the water-insoluble diluent having a particle size (d90) of about 98 μm to about 229 μm corresponding to 90% in a cumulative particles size distribution of total particles.
Inventors:
SONG HAN BYUL (KR)
CHO JUNG HYUN (KR)
KIM JIN CHEUL (KR)
KIM YOUG IL (KR)
PARK JAE HYUN (KR)
WOO JONG SOO (KR)
CHO JUNG HYUN (KR)
KIM JIN CHEUL (KR)
KIM YOUG IL (KR)
PARK JAE HYUN (KR)
WOO JONG SOO (KR)
Application Number:
PCT/KR2017/013508
Publication Date:
June 07, 2018
Filing Date:
November 24, 2017
Export Citation:
Assignee:
HANMI PHARM IND CO LTD (KR)
International Classes:
A61K9/20; A61K31/397; A61K31/505
Domestic Patent References:
| WO2009024889A2 | 2009-02-26 |
Foreign References:
| KR20160000762A | 2016-01-05 | |||
| KR20150079454A | 2015-07-08 | |||
| KR20160105044A | 2016-09-06 | |||
| US20140287042A1 | 2014-09-25 |
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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