ORAL DEVICES AND METHODS FOR CONTROLLED DRUG DELIVERY

Title:

ORAL DEVICES AND METHODS FOR CONTROLLED DRUG DELIVERY

Document Type and Number:

WIPO Patent Application WO2004069076

Kind Code:

A3

Abstract:

Controlled-drug-delivery oral devices are implanted or inserted into an oral cavity, built onto a prosthetic tooth crown, a denture plate, braces, a dental implant, or the like. The devices are refilled or replaced as needed. The controlled drug delivery may be passive, based on a dosage form, or electro-mechanically controlled, for a high-precision, intelligent, drug delivery. Additionally, the controlled delivery method may vary and depend on a variety of factors. Drug absorption in the oral cavity may be assisted or induced by a transport mechanism. The oral devices require refilling or replacement at relatively long intervals of weeks or months, maintain a desired dosage level in the oral cavity, hence in the gastrointestinal tract, for extended periods, address situations of narrow drug therapeutic indices, and by being automatic, ensure adherence to a prescribed medication regimen. The oral devices and methods for controlled drug delivery apply to humans and animals.

Inventors:

WOLFF ANDY (IL)
BEISKI BEN Z (IL)
SELA YORAM (IL)

Application Number:

PCT/IL2004/000123

Publication Date:

November 30, 2006

Filing Date:

February 08, 2004

Export Citation:

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Assignee:

WOLFF ANDY (IL)
BEISKI BEN Z (IL)
SELA YORAM (IL)

International Classes:

A61M31/00; A61C19/06; A61J7/00; A61K9/22

Foreign References:

US5196002A	1993-03-23
US6127410A	2000-10-03
US4871351A	1989-10-03

Other References: