ORAL DOSAGE FORM SAFEGUARDED AGAINST ABUSE

Title:

ORAL DOSAGE FORM SAFEGUARDED AGAINST ABUSE

Document Type and Number:

WIPO Patent Application WO2006002884

Kind Code:

B1

Abstract:

The invention relates to an oral dosage form, which is safeguarded against abuse and which has a controlled opioid release for a once daily administering. The invention is characterized in that the oral dosage form comprises at least one opioid with an abuse potential (A), at least one synthetic and/or natural polymer (C), optionally comprises retarding matrix materials, physiologically compatible adjuvants (B), optionally comprises a wax (D), and optionally comprises at least one retarding coating. Constituents (C) or (D) each have a breaking resistance of at least 500 N, preferably at least 750 N.

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Inventors:

BARTHOLOMAEUS JOHANNES (DE)
KUGELMANN HEINRICH (DE)

Application Number:

PCT/EP2005/006984

Publication Date:

March 02, 2006

Filing Date:

June 29, 2005

Export Citation:

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Assignee:

GRUENENTHAL GMBH (DE)
BARTHOLOMAEUS JOHANNES (DE)
KUGELMANN HEINRICH (DE)

International Classes:

(IPC1-7): A61K9/22; A61K31/135

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