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Title:
ORAL FLORA-IMPROVING AGENT, ANTIBACTERIAL AGENT AND GROWTH PROMOTER
Document Type and Number:
WIPO Patent Application WO/2005/107769
Kind Code:
A1
Abstract:
It is intended to provide an oral flora-improving agent capable of forming a favorable flora in the oral cavity and a food or a drink for improving the oral flora. An oral flora-improving agent comprising a ganglioside as the active ingredient and a food, a drink or a feed for improving the oral flora containing a ganglioside exhibit an antibacterial effect on harmful bacteria in the oral cavity, which are undesirable from the viewpoint of decay and diseases such as periodontal disease, and a growth-promoting effect on useful bacteria to be preserved in the oral cavity. Moreover, a ganglioside is efficaciously usable in an antibacterial agent, an antibacterial food, drink or feed, a growth promoter or a food, a drink or a feed for promoting growth.

Inventors:
KAWAKAMI HIROSHI (JP)
HANADA NOBUHIRO (JP)
IMAI SUSUMU (JP)
Application Number:
PCT/JP2005/008348
Publication Date:
November 17, 2005
Filing Date:
May 06, 2005
Export Citation:
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Assignee:
SNOW BRAND MILK PRODUCTS CO LTD (JP)
KAWAKAMI HIROSHI (JP)
HANADA NOBUHIRO (JP)
IMAI SUSUMU (JP)
International Classes:
A23K20/195; A23L2/00; A23L2/52; A61K8/00; A61K8/60; A61K8/68; A61K8/73; A61K31/7028; A61P1/02; A61P31/04; A61Q11/00; C07H15/10; (IPC1-7): A61K31/7028; A23K1/16; A23L1/30; A23L2/00; A61K7/16; A61P1/02; A61P31/04; C07H15/10
Domestic Patent References:
WO2002040051A12002-05-23
Foreign References:
JPH11209756A1999-08-03
JP2001158735A2001-06-12
JPS6084296A1985-05-13
GB1269846A1972-04-06
Other References:
SCHWAB U ET AL: "Binding of Staphylococcus aureus to fibronectin and glycolipids on corneal surfaces.", GERMAN JOURNAL OF OPHTHALMOLOGY., vol. 5, no. 6, November 1996 (1996-11-01), pages 417 - 421, XP002994271
KAWAKAMI H ET AL: "Milk Yurai Sialic Acid Ganku Seibun no Seitai Bogyo Kino- Ikujiyo Chosei Funnyu eno Oyo-.", GEKKAN MEDICAL SCIENCE DIGEST., vol. 29, no. 13, 2003, pages 532 - 533, XP002994272
LEKHOLM U ET AL: "GANGLIOSIDES IN HUMAN PALATAL ORAL EPITHELIUM.", ARCHIVES OF ORAL BIOLOGY., vol. 24, no. 1, 1979, pages 47 - 52, XP002994273
See also references of EP 1747783A4
Attorney, Agent or Firm:
Fujino, Seiya (7-7 Toranomon 2-chom, Minato-ku Tokyo 01, JP)
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