Title:
ORAL POLYSACCHARIDE FOR TREATING INFLAMMATORY BOWEL DISEASE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/097925
Kind Code:
A1
Abstract:
The present application relates to a preparation method for a refined heparin polysaccharide. Raw materials of the heparin polysaccharide are separated by means of size exclusion chromatography, and the collected separated components are subjected to treatments such as freeze-drying, alcohol precipitation, and desalination so as to obtain a refined heparin polysaccharide product. The present application further relates to an oligosaccharide having specific polysaccharide structural features and anti-UC effectiveness, which can be used for prevention and treatment of inflammatory bowel disease, complications related to inflammatory bowel disease, and diseases having similar pathogenesis. The present application further relates to an oligosaccharide having specific polysaccharide structural features and anti-inflammatory effectiveness.
Inventors:
XING XINHUI (CN)
WANG YI (CN)
ZENG WEN (CN)
ZHANG CHONG (CN)
WANG YI (CN)
ZENG WEN (CN)
ZHANG CHONG (CN)
Application Number:
PCT/CN2022/080641
Publication Date:
June 08, 2023
Filing Date:
March 14, 2022
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
International Classes:
A61K31/727; C12P19/00; A61P1/00; A61P19/02; C08B37/10
Foreign References:
| CN108424475A | 2018-08-21 | |||
| CN1712418A | 2005-12-28 | |||
| CN102277396A | 2011-12-14 | |||
| CN1429913A | 2003-07-16 | |||
| CN1819833A | 2006-08-16 |
Attorney, Agent or Firm:
BEIJING CAI HE LAW FIRM (CN)
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