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Patent Searching and Data


Title:
ORAL TUMOR VACCINE
Document Type and Number:
WIPO Patent Application WO/2016/208332
Kind Code:
A1
Abstract:
A tumor vaccine that can be administered orally can be provided using a transformed bifidobacterium which can express/present WT1 protein. WT1 protein expressed/presented by the transformed bifidobacterium is a protein which can cover a major portion of WT1 protein, unlike a WT1 peptide vaccine that is constrained by a specific type of HLA. A tumor vaccine containing the transformed bifidobacterium as an active ingredient can be applied to patients having various HLA types.

Inventors:
SHIRAKAWA TOSHIRO (JP)
KATAYAMA TAKANE (JP)
HASHII YOSHIKO (JP)
OZONO KEIICHI (JP)
Application Number:
PCT/JP2016/065922
Publication Date:
December 29, 2016
Filing Date:
May 30, 2016
Export Citation:
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Assignee:
NAT UNIV CORP KOBE UNIV (JP)
UNIV OSAKA (JP)
International Classes:
C12N1/21; A61K35/745; A61K38/00; A61P35/00; C07K19/00; C12N15/09; C07K14/195; C07K14/82
Domestic Patent References:
WO2011034181A12011-03-24
WO2014129412A12014-08-28
WO2014173542A12014-10-30
WO2013106834A22013-07-18
WO2007047764A22007-04-26
Other References:
KITAGAWA K. ET AL.: "Development of the novel oral tumor vaccine using bifidobacterium longum displaying Wilms' tumor 1 protein", MOLECULAR THERAPY, vol. 24, no. suppl. 1, pages s157, XP055340052
See also references of EP 3315599A4
Attorney, Agent or Firm:
SHOJI, Takashi et al. (JP)
Takashi Shoji (JP)
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