Title:
ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE
Document Type and Number:
WIPO Patent Application WO/2014/129616
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. Accordingly, an orally administered adsorbent is characterized by including spherical active carbon which has: an average bulk density of 0.4-0.6 g/mL; and a volume of pores having diameters in the range 1.5-2.0 nm, said volume being obtained using the Saito-Foley (SF) method by way of nitrogen adsorption, which satisfies formula (1), namely y > 6×10-8x2-9×10-5x+0.0241 (in formula (1): y represents the volume (mL/g) of pores having diameters in the range 1.5-2.0 nm, said volume being obtained using the SF method by way of nitrogen adsorption; and x represents the Brunauer-Emmett-Teller (BET) specific surface area (m2/g)).
Inventors:
SONOBE NAOHIRO (JP)
WAKAHOI TAKASHI (JP)
AKITA TAKAHIRO (JP)
GOTO MASAKO (JP)
WAKAHOI TAKASHI (JP)
AKITA TAKAHIRO (JP)
GOTO MASAKO (JP)
Application Number:
PCT/JP2014/054263
Publication Date:
August 28, 2014
Filing Date:
February 24, 2014
Export Citation:
Assignee:
KUREHA CORP (JP)
International Classes:
A61K33/44; A61P1/16; A61P13/12; A61P39/02
Domestic Patent References:
| WO2005094844A1 | 2005-10-13 | |||
| WO2005094845A1 | 2005-10-13 | |||
| WO2010086985A1 | 2010-08-05 |
Attorney, Agent or Firm:
MORITA Kenichi et al. (JP)
Ken-ichi Morita (JP)
Ken-ichi Morita (JP)
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