ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE

WIPO Patent Application WO/2014/129618

A1

The purpose of the present invention is to provide surface-modified spherical active carbon exhibiting excellent adsorption capacity with respect to uremic substances in the body, and particularly with respect to β-aminoisobutyric acid. Accordingly, provided is an orally administered adsorbent characterized by including surface-modified spherical active carbon which includes at least 0.5 wt% of nitrogen, and which has a specific surface area obtained using the Brunauer-Emmett-Teller (BET) method of 800-3000 m2/g, an average particle size of 0.01-1 mm, and a total acid group content of at least 0.30 meq/g.

WAKAHOI TAKASHI (JP)
AKITA TAKAHIRO (JP)
SONOBE NAOHIRO (JP)
KUWAHARA MIEKO (JP)

PCT/JP2014/054265

August 28, 2014

February 24, 2014

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KUREHA CORP (JP)

A61K33/44; A61K31/785; A61P1/16; A61P13/12; A61P39/02

WO2005094845A1

2005-10-13

JP2004168587A	2004-06-17
JP2009056449A	2009-03-19
JP2009269765A	2009-11-19
JPS6211611B2	1987-03-13
JP2005314416A	2005-11-10

BOKI, K. ET AL.: "Removal by Adsorption of Hydrogen Sulfide by a New Type of Activated Carbon Containing Nitrogen", JAPANESE JOURNAL OF HYGIENE, vol. 38, no. 5, 1983, pages 877 - 882, XP055273814
N. HONDA; K. KOISO; K. KUROGAWA: "Clinical Nephrology", 1990, ASAKURA PUBLISHING
"Nephrology", 1981, IGAKU SHOIN
See also references of EP 2959908A4

MORITA Kenichi et al. (JP)
Ken-ichi Morita (JP)

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