Title:
ORGAN TOXICITY DIAGNOSTIC BIOMARKER COMPOSITION COMPRISING EXOSOME OR PROTEIN OF SAME AND DIAGNOSTIC METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2016/140388
Kind Code:
A1
Abstract:
The present invention relates to an organ toxicity diagnostic biomarker composition comprising exosome or a protein of same, an organ toxicity diagnostic composition comprising a formulation for detecting exosome or a protein of same, an organ toxicity diagnostic kit comprising the composition, a method for providing information for organ toxicity diagnosis using the composition, and a method for screening an organ toxicity therapeutic material comprising the composition. By using exosome according to the present invention, organ toxicity can be quickly diagnosed and, in particular, toxicity of a particular organ can be diagnosed by using an organ-specific exosome protein. Therefore, the present invention can be utilized for accurate and quick diagnosis or prognosis of organ toxicity due to various drugs.
Inventors:
BAEK MOON CHANG (KR)
CHO YOUNG EUN (KR)
CHO YOUNG EUN (KR)
Application Number:
PCT/KR2015/002145
Publication Date:
September 09, 2016
Filing Date:
March 05, 2015
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV INDUSTRY-ACADEMIC COOP FOUND (KR)
International Classes:
G01N33/53; G01N33/68
Domestic Patent References:
| WO2011083145A1 | 2011-07-14 |
Foreign References:
| US20130005599A1 | 2013-01-03 | |||
| KR20140076571A | 2014-06-20 | |||
| JP2013188212A | 2013-09-26 |
Other References:
SIMPSON, JEREMY A. ET AL.: "Differential Detection of Skeletal Troponin lisoforms in Serum of a Patient with Rhabdomyolysis: Markers of Muscle Injury?", CLINICAL CHEMISTRY, vol. 48, no. 7, 2002, pages 1112 - 1114, XP002275173
Attorney, Agent or Firm:
KIM, SOON WOONG (KR)
κΉμμ (KR)
κΉμμ (KR)
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