Title:
ORGANOID PRODUCED USING CARRIER FOR CELL CULTURE, AND METHOD FOR EVALUATING DRUG TOXICITY USING SAME
Document Type and Number:
WIPO Patent Application WO/2020/101461
Kind Code:
A1
Abstract:
The present invention relates to an organoid and, more specifically, to an organoid and a use thereof, the organoid being produced using a carrier for cell culture which comprises microcapsules containing gelatin, a natural polymer, an oil, and an oil thickener. When used as a carrier for cell culture in culturing cells, the microcapsules containing a natural oil, according to the present invention, have the effects of improving adhesion and survival of the cells and inducing maturation of the cultured cells. The organoid produced by culturing cells using the carrier for cell culture has been confirmed to have the function of the organ concerned and, when treated with a drug, react to the toxicity of the drug and thus can be variously employed in the development of new drugs, disease research, and the field of artificial organ development.
Inventors:
KANG SUN WOONG (KR)
SHIM HYE EUN (KR)
SHIM HYE EUN (KR)
Application Number:
PCT/KR2019/095042
Publication Date:
May 22, 2020
Filing Date:
November 12, 2019
Export Citation:
Assignee:
KOREA RES INST CHEMICAL TECH (KR)
International Classes:
C12N5/00; C12N5/077; G01N33/50
Domestic Patent References:
| WO2015173425A1 | 2015-11-19 |
Foreign References:
| CN1485094A | 2004-03-31 | |||
| US5693343A | 1997-12-02 | |||
| CN1641017A | 2005-07-20 | |||
| US5051304A | 1991-09-24 | |||
| JP2007215519A | 2007-08-30 |
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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