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Title:
ORTHOGONAL ACCELERATION TIME-OF-FLIGHT MASS SPECTROMETER
Document Type and Number:
WIPO Patent Application WO/2019/211918
Kind Code:
A1
Abstract:
According to the present invention, when a user specifies, via an input unit (54), a mass range of a mass spectrum desired for observation, a CES analysis control unit (51) controls respective components so that MS/MS analysis is conducted while sequentially varying collision energy to a plurality of predetermined values. Here, a delay time from the time at which ions are discharged from a collision cell (13) until the time at which the ions are accelerated by an orthogonal accelerator (17) is determined in accordance with the mass range. In the interior space of an ion guide (14), a gradient of the depth of a potential is formed in the direction of ion travel, thereby enabling achieving of a high ion accumulation effect over a broad m/z range. The upper limit of this m/z range is dependent on the delay time, and therefore, by determining the delay time according to the mass range, it is possible to reliably achieve a high detection sensitivity within the m/z range of that particular mass range. As a result, it becomes possible to produce a preferable mass spectrum that enables observation of a variety of product ions generated from dissociation under different collision energies.

Inventors:
OSHIRO, Tomoyuki (1 Nishinokyo-Kuwabara-cho, Nakagyo-ku, Kyoto-sh, Kyoto 11, 〒6048511, JP)
Application Number:
JP2018/017566
Publication Date:
November 07, 2019
Filing Date:
May 02, 2018
Export Citation:
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Assignee:
SHIMADZU CORPORATION (1 Nishinokyo-Kuwabara-cho, Nakagyo-ku Kyoto-sh, Kyoto 11, 〒6048511, JP)
International Classes:
H01J49/40
Domestic Patent References:
WO2017122339A12017-07-20
WO2017017787A12017-02-02
Attorney, Agent or Firm:
KYOTO INTERNATIONAL PATENT LAW OFFICE (Hougen-Sizyokarasuma Building, 37 Motoakuozi-tyo, Higasinotouin Sizyo-sagaru, Simogyo-ku, Kyoto-s, Kyoto 91, 〒6008091, JP)
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