[0001] This application claims the benefit of US Provisional Application No.

61/868,667, filed on August 22, 2013, pending, which is incorporated herein by reference.

TECHNICAL FIELD

[0002] The present disclosure relates to a respiratory treatment device, and in particular, to an oscillating positive respiratory pressure device.

BACKGROUND

[0003] Each day, humans may produce upwards of 30 milliliters of sputum, which is a type of bronchial secretion. Normally, an effective cough is sufficient to loosen secretions and clear them from the body's airways. However, for individuals suffering from more significant bronchial obstructions, such as collapsed airways, a single cough may be insufficient to clear the obstructions.

[0004] One type of therapy, utilizing oscillating positive expiratory pressure

("OPEP"), is often used to address this issue. OPEP therapy represents an effective bronchial hygiene technique for the removal of bronchial secretions in the human body and is an important aspect in the treatment and continuing care of patients with bronchial obstructions, such as those suffering from chronic obstructive lung disease. It is believed that OPEP therapy, or the oscillation of exhalation pressure at the mouth during exhalation, effectively transmits an oscillating back pressure to the lungs, thereby splitting open obstructed airways and loosening the secretions contributing to bronchial obstructions.

[0005] OPEP therapy is an attractive form of treatment because it can be easily taught to most hospitalized patients, and such patients can assume responsibility for the administration of OPEP therapy throughout their hospitalization and also once they have returned home. To that end, a number of portable OPEP devices have been developed.

BRIEF SUMMARY

[0006] In one aspect, a respiratory treatment device includes a housing enclosing a chamber, a chamber inlet configured to receive a flow of air into the chamber, a first chamber outlet configured to permit the flow of air to exit the chamber, and a second chamber outlet configured to permit the flow of air to exit the chamber. A vane mounted within the chamber is configured to rotate between a first position where the flow of air is directed to exit the chamber through the first chamber outlet, and a second position where the flow of air is directed to exit the chamber through the second chamber outlet. A blocking member disposed on the vane is moveable relative to the chamber inlet between a closed position where the flow of air through the chamber inlet is restricted, and an open position where the flow of air through the chamber inlet is less restricted.

[0007] In another aspect, the vane may be configured to rotate in response to the flow of air into the chamber. The vane may be configured to repeatedly reciprocate between the first position and the second position in response to the flow of air into the chamber. The vane may also be prohibited from completing a complete revolution.

[0008] In another aspect, a size of the blocking member may be greater than a size of the chamber inlet. Alternatively, a size of the blocking member may be less than a size of the chamber inlet.

[0009] In another aspect, an axis of rotation of the vane may be offset from a center of the vane.

[0010] In another aspect, the respiratory treatment also includes a mouthpiece, wherein a cross sectional area of the mouthpiece is larger than a cross sectional area of the chamber inlet. In addition, an inhalation port may be in communication with the mouthpiece, the inhalation port having a one-way valve configured to open upon inhalation and close upon exhalation. [0011] In yet another aspect, a respiratory treatment device includes a housing enclosing a chamber, an inlet configured to receive a flow of air into the chamber, and an outlet configured to permit the flow of air to exit chamber. A blocking member mounted in the chamber is moveable relative to the chamber outlet between a closed position where the flow of air through the exit is restricted, and an open position where the flow of air through the chamber outlet is less restricted. At least one vane rotatably mounted in the chamber is configured to move the blocking member between the closed position and the open position in response to the flow of air into the chamber.

[0012] In another aspect, the blocking member may be connected to the at least one vane by a shaft and at least one linkage. The shaft and the at least one linkage may cooperate to move the blocking member in linear reciprocating motion.

[0013] In another aspect, the blocking member may be configured to move between the open position and the closed position in response to contact from an arm connected to the at least one vane.

[0014] In another aspect, the blocking member may be biased toward the open position.

[0015] In another aspect, the at least one vane comprises a turbine having a plurality of vanes.

[0016] In another aspect, the chamber comprises a first portion enclosing the at least one vane and a second portion enclosing the blocking member. The first portion may be in communication with the second portion.

[0017] In another aspect, the respiratory treatment also includes a mouthpiece, wherein a cross sectional area of the mouthpiece is larger than a cross sectional area of the chamber inlet. In addition, an inhalation port may be in communication with the mouthpiece, the inhalation port having a one-way valve configured to open upon inhalation and close upon exhalation.

[0018] In yet another aspect, a method of performing respiratory treatment includes receiving a flow of air into a device having an inlet configured to receive a flow of air into the device, a first outlet configured to permit the flow air to exit the device, and a second outlet configured to permit the flow of air to exit the device. The method further includes rotating a vane mounted within the device repeatedly between a first position where the flow of air is directed to exit the chamber through the first chamber outlet, and a second position where the flow of air is directed to exit the chamber through the second chamber outlet. The method also includes moving a blocking member disposed on the vane relative to the chamber inlet between a closed position where the flow of air through the chamber inlet is restricted, and an open position where the flow of air through the chamber inlet is less restricted.

BRIEF DESCRIPTION

[0019] FIG. 1 is a front perspective view of a first embodiment of an OPEP device;

[0020] FIG. 2 is a rear perspective view of the OPEP device of FIG. 1 ;

[0021] FIG. 3 is a cross-sectional perspective view of the OPEP device of FIG. 1 ;

[0022] FIG. 4 is a perspective view of a blocking member disposed on a vane mountable within the OPEP device of FIG. 1 ;

[0023] FIGS. 5A-5E are cross-sectional views illustrating the operation of the OPEP device of FIG. 1 ;

[0024] FIGS. 6A-6F are cross-section views illustrating exemplary modifications to the OPEP device of FIG. 1 ;

[0025] FIG. 7 is a front perspective view of a second embodiment of an OPEP device;

[0026] FIG. 8 is a rear perspective view of the OPEP device of FIG. 7;

[0027] FIG. 9 is a perspective view of the OPEP device of FIG. 7, shown with a font cover of the device removed;

[0028] FIG. 10 is a cross-sectional view of the OPEP device of FIG. 7;

[0029] FIG. 11 is a perspective view of the OPEP device of FIG. 7, shown with the front cover of the device removed;

[0030] Fig. 12 is a perspective view of the OPEP device of the FIG. 7, shown with a rear cover of the device removed, and with a blocking member in an open position; [0031] FIG. 13 is a perspective view of the OPEP device of FIG. 7, shown with the rear cover of the device removed, and with the blocking member in a closed position;

[0032] FIG. 14 is a front perspective view of a third embodiment of an OPEP device;

[0033] FIG. 15 is a rear perspective view of the OPEP device of FIG. 14;

[0034] FIG. 16 is an exploded view of the OPEP device of FIG. 14;

[0035] FIG. 17 is a perspective view of an assembly of the internal components of the OPEP device of FIG. 14;

[0036] FIG. 18 is a cross-sectional view of the OPEP device of FIG. 14; and,

[0037] FIG. 19 is a perspective view of a one-way valve usable in the OPEP device of FIG. 14.

DETAILED DESCRIPTION

[0038] Referring to FIGS. 1-4, a first embodiment of an OPEP device 100 is shown. In general, the OPEP device 100 includes a housing 102 enclosing a chamber 104, a chamber inlet 106, a first chamber outlet 108, a second chamber outlet 1 10, a mouthpiece 112 in communication with the chamber inlet 106, a vane 1 14 mounted within the chamber 104, and a blocking member 1 16 disposed on the vane 114.

[0039] The housing 102 and OPEP device 100 components may be constructed of any durable material, such as a low friction plastic or polymer, and may include a front section 103 and a rear section 105 that are removably attachable such that the chamber 104 may be periodically accessed for cleaning and/or replacement of the vane 114. In addition, although the mouthpiece 112 is shown as being fixedly attached to the housing 102, it is envisioned that the mouthpiece 112 may be removeable and replaceable with a mouthpiece of a different shape or size. Preferably, the size or cross-sectional area of the mouthpiece 1 12 is greater than the size or cross-sectional area of the chamber inlet 106. It is envisioned that other user interfaces, such as breathing tubes or gas masks (not shown), may alternatively be associated with the housing 102.

[0040] As shown in FIG. 3, the vane 114 is rotatably mounted within the chamber 104 about a shaft 1 18. The shaft 1 18 may be supported by bearings 120a, 120b formed in the housing 102. As shown in FIG. 4, the vane 114 is formed as a generally planar member adapted for rotation about the shaft 118 positioned at the center of the vane 1 14. Alternatively, the vane 1 14 could be formed with any number of curves or contours. A blocking member 1 16 is disposed on an end of the vane 1 14 and is adapted to move relative to the chamber inlet 106 between an closed position, where the flow of air through the chamber inlet 106 is restricted by the blocking member 116, and an open position where the flow of air through the chamber inlet 106 is less restricted. As shown, the blocking member 116 is curved, such that it may travel in close proximity to the chamber inlet 106. The blocking member 1 16 is also sized and shaped such that the flow of air through the chamber inlet 106 may be completed restricted when the blocking member 1 16 is in a closed position. As discussed below, it is envisioned that the blocking member 116 and/or the chamber inlet 106 could be any number of shapes and sizes, and that the blocking member 1 16 may only partially restrict the flow of air through the chamber inlet 106 when the blocking member 116 is in a closed position.

[0041] The operation of the OPEP device 100 will now be described with reference to the illustrations shown in FIGS. 5A-5E. In FIGS. 5A-5E, the flow of air through the device 100 is illustrated by dashed lines. However, it should be appreciated that the dashed lines are exemplary and provided for purposes of illustration. The actual flow air through the device 100 may traverse any number of flow paths.

[0042] As shown in FIG. 5A, administration of OPEP therapy using the OPEP device 100 begins with the vane 114 in a first position, and the blocking member 1 16 in an open position. With the vane 114 in this position, exhaled air flowing into the

mouthpiece 1 12 enters the chamber 104 through the chamber inlet 106, where it is directed by the vane 114 toward the rear portion of the of the chamber 104, denoted in FIG. 5A by "X", and generally toward the first chamber outlet 108. Although some of the exhaled air exits the OPEP device 100 through the first chamber outlet 108, as a user continues to exhale, the pressure in the rear portion of the chamber 104 increases, causing the vane 114 to begin to rotate in a clockwise direction. [0043] As a user continues to exhale, the vane 1 14 rotates from the position shown in FIG. 5A to the position shown in FIG 5B. In this position, exhaled air flowing into the chamber 104 may exit the chamber 104 through the first chamber exit 108, or flow around the vane 1 14 and exit the chamber 104 through the second chamber exit 1 10. The blocking member 116 in this position is also partially restricting the flow of air through the chamber inlet 106, thereby causing the pressure in the mouthpiece 112 to increase. In this position, some of the exhaled air exits the OPEP device 100 through the first chamber outlet 108. However, as a user continues to exhale, pressure in the rear of the chamber 104, along with the flow of air around the vane 1 14, cause the vane 114 to continue to rotate in a clockwise direction.

[0044] As a user continues to exhale, the vane 1 14 rotates from the position shown in FIG. 5B to the position shown in FIG. 5C. In this position, the blocking member 116 is in a closed position, and exhaled air is completely restricted from flowing through the chamber inlet 106 into the chamber 104, thereby causing the pressure in the

mouthpiece 1 12 to rapidly increase. In this position, the momentum of the vane 114 and the blocking member 116 continue to drive the vane 1 14 in a clockwise direction.

[0045] As the vane 114 continues to rotate in a clockwise direction, the vane 1 14 rotates from the position shown in FIG. 5C to the position shown in FIG. 5D. In this position, exhaled air flowing into the chamber 104 may exit the chamber 104 through the second chamber exit 1 10, or flow around the vane 1 14 and exit the chamber 04 through the first chamber exit 108. In this position, the momentum of the vane 1 14 and the blocking member 1 16 is sufficient to overcome any opposing forces and continue rotating the vane 1 14 in a clockwise direction.

[0046] As the vane 114 continues to rotate in a clockwise direction, the vane 1 14 rotates from the position shown in FIG. 5D to the position shown in FIG. 5E. Additional rotation of the vane 114 is prevented if the vane 114 contacts the housing 102. With the vane 114 in this position, exhaled air flowing into the mouthpiece 1 12 enters the chamber 104 through the chamber inlet 106, where it is directed by the vane 1 14 toward the rear portion of the of the chamber 104, denoted in FIG. 5E by "X", and generally toward the second chamber outlet 110. Although some of the exhaled air exits the OPEP device 100 through the second chamber outlet 1 10, as a user continues to exhale, the pressure in the rear portion of the chamber 104 increases, causing the vane 14 to begin to rotate in a counter clockwise direction, repeating the cycle described above, although in reverse order.

[0047] During a period of exhalation, the vane 1 14 rotates repeatedly between the first position and the second position in clockwise and counter-counterclockwise directions. As this movement is repeated, the blocking member 1 16 moves repeatedly between a closed position, where the flow of air through the chamber inlet 106 is restricted by the blocking member 1 16, and an open position, where the flow of air through the chamber inlet 106 is less restricted. Consequently, the pressure in the mouthpiece 1 12, or user interface, oscillates between a higher pressure and a lower pressure, which pressures are in turn transmitted to the user's airways, thereby administering OPEP therapy.

[0048] Turning to FIGS. 6A-6F, various modifications to the OPEP device 100 are shown. As shown in FIGS. 6A and 6B, exemplary modifications to the chamber inlet 106 are shown. Whereas the chamber inlet 106 shown in FIG. 3 is sized and shaped as a long and narrow horizontal opening, as shown in FIG. 6A, a chamber inlet 106' may be sized and shaped as a long and narrow opening, or as shown in FIG. 6B, a chamber inlet 106" may be sized and shaped as two narrow openings. It is also envisioned that the opening could be shaped as a cross, a circle, a square, or any other number of shapes, or combination of shapes. In this way, the shape and size of the chamber inlet 106 may be selected to achieve the desired performance of the OPEP device 100.

[0049] As shown in FIGS. 6C-6F, exemplary modification to the vane 1 14 and the blocking member 1 16 are shown. For example, as compared to the blocking member 1 16 shown in FIGS. 3-4, a blocking member 1 16' shown in FIG. 6C is larger, thereby restricting the flow of air through the chamber inlet 106 for a longer period while the blocking member 116' is in a closed position. Similarly, as compared to the vane 114 shown in FIGS. 3-4, a vane 1 14' and a vane 114" are shorter in length, thereby changing the speed or frequency at which the vanes rotate, and the pressures at which the OPEP device 100 operates. In general, a shorter vane will oscillate faster, while a longer vane will oscillate slower. Finally, as shown in FIG. 6F, a vane 14"' is configured to have an axis of rotation, or the position of the shaft 118, offset from a center of the vane 114"'. It is also envisioned that the total rotation of a vane may be selected or adjusted, for example, by changing the length of the vane while maintaining the size of the housing, or by providing a stop in the housing that limits the rotation of the vane. In general, an increase in the amount of rotation will result in a decreased frequency, while a decrease in the amount of rotation will result in an increased frequency.

[0050] Referring to FIGS. 7-13, a second embodiment of an OPEP device 200 is shown. In general, the OPEP device 200 includes a housing 202 enclosing a chamber 204 having a first portion 207 and a second portion 209 joined by a passage 211 , a chamber inlet 206, a chamber outlet 208, a mouthpiece 212 in communication with the chamber inlet 206, a turbine 214 rotatably mounted within the chamber 204 via a shaft 218, a blocking member 216, a first linkage 220, and a second linkage 222.

[0051] The housing 202 and OPEP device 200 components may be constructed of any durable material, such as a low friction plastic or polymer, and may include a front cover 203 and a rear cover 205 that are removably attachable such that the chamber 204 may be periodically accessed for cleaning and/or replacement of the turbine 214 and/or linkages 220, 222. In addition, although the mouthpiece 212 is shown as being fixedly attached to the housing 202, it is envisioned that the mouthpiece 212 may be removeable and replaceable with a mouthpiece of a different shape or size. Preferably, the size or cross-sectional area of the mouthpiece 212 is greater than the size or cross- sectional area of the chamber inlet 206. It is envisioned that other user interfaces, such as breathing tubes or gas masks (not shown), may alternatively be associated with the housing 202. [0052] As shown in FIGS. 9-11 , the turbine 214 is rotatably mounted via the shaft 218 within the first portion 207 of the chamber 204 and is configured to rotate in response to a flow of air through the chamber inlet 206. As shown, the turbine 214 includes a plurality of vanes, although it is envisioned that the turbine could have as few as one vane, or many more vanes. The size and shape of the vanes may also vary.

[0053] As shown in FIGS. 12-13, the first linkage 220, the second linkage 222, and the blocking member 216 are mounted within the second portion 209 of the chamber 204. The first linkage 220 is fixed about one end to the shaft 218, and as such, is configured to rotate in unison with the turbine 214. The second linkage 222 is hinged to the other end of the first linkage 220, as well as the blocking member 216. The blocking member 216 is surrounded by and in sliding engagement with a first pair and a second pair of guide rails 224, 226. In this way, rotation of the turbine 214 and shaft 218 causes rotation of the first linkage 220, translation and rotation of the second linkage 222, and ultimately, linear translation or reciprocation of the blocking member 216 between the position shown in FIG. 12 and the position shown in FIG. 13. In the position shown in FIG. 13, the blocking member 216 is in a closed position, where the flow of air through the chamber outlet 208 (seen in FIG. 8) is restricted by the blocking member 216, whereas, in the position shown in FIG. 12, the blocking member 216 is in a closed position, where the flow of air through the chamber outlet 208 is less restricted. It should be appreciated that the blocking member 216 may completely or partially restrict the flow of air through the chamber outlet 208 when the blocking member 216 is in a closed position.

[0054] The operation of the OPEP device 200 will now be described with reference to the illustrations shown in FIGS. 9-13. In FIGS. 9-13, the flow of air through the device 200 is illustrated by dashed lines. However, it should be appreciated that the dashed lines are exemplary and provided for purposes of illustration. The actual flow air through the device 200 may traverse any number of flow paths.

[0055] In general, administration of OPEP therapy using the OPEP device 200 begins with the blocking member 216 in an open position, as shown in FIG. 12. With the blocking member 216 in this position, as a user exhales into the mouthpiece 212, or user interface, exhaled air flows into the chamber 204 through the chamber inlet 206. In response to the flow of air through the chamber inlet 206, the turbine 214 begins to rotate, allowing the air to flow between the chamber inlet 206 and the passage 21 1 connecting the first portion 207 of the chamber with the second portion 209 of the chamber 204. Because the first linkage 202 is operatively connected to the turbine 214 via the shaft 218, rotation of the turbine 214 results in rotation of the first linkage 202, which in turn causing the second linkage 222 to rotate relative to the first linkage 220 and the blocking member 216, as the blocking member 216 is driven between an open position, shown in FIG. 12, and a closed position, shown in FIG. 13. As the blocking member 216 is moved from an open position shown in FIG. 12 to a closed position shown in FIG. 13, the air flowing from the passage 211 through the second portion 209 of the chamber 204 is restricted from exiting the chamber 204 through the chamber outlet 208, thereby causing the pressure throughout the device 200 to increase. As a user continues to exhale, and the turbine 214 continues to rotate, the blocking member 216 returns to an open position, allowing the air in the chamber 204 to exit the chamber 204 through the chamber outlet 208, resulting in a decrease in pressure throughout the device 200. During a period of exhalation, the blocking member 216 reciprocates repeatedly between an open position and a closed position, causing the pressure in the device to oscillate between a lower pressure and a higher pressure, which is in turn transmitted to the user's airways, thereby administering OPEP therapy.

[0056] Turning to FIGS. 14-19, a third embodiment of an OPEP device 300 is shown. In general, the OPEP device 300 includes a housing 302 enclosing a chamber 304, a chamber inlet 308, a chamber outlet 308, a vent 338, a mouthpiece 312 in

communication with the chamber inlet 306, a turbine 314 rotatably mounted within the chamber 304 via a shaft 318, a blocking member 316, and a pair of arms 320, 322 operatively connected to the shaft 318.

[0057] The housing 302 and OPEP device 300 components may be constructed of any durable material, such as a low friction plastic or polymer, and may include an upper section 303, an inner section 301 , and a lower section 305 that are removably attachable such that the chamber 304 may be periodically accessed for cleaning and/or replacement of the turbine 314. In addition, although the mouthpiece 312 is shown as being fixedly attached to the housing 302, it is envisioned that the mouthpiece 312 may be removeable and replaceable with a mouthpiece of a different shape or size.

Preferably, the size or cross-sectional area of the mouthpiece 312 is greater than the size or cross-sectional area of the chamber inlet 306. It is envisioned that other user interfaces, such as breathing tubes or gas masks (not shown), may alternatively be associated with the housing 302.

[0058] Turning to FIG. 17, an assembly of internal components of the OPEP device 300 includes the turbine 314, the inner section 301 of the housing 302, the pair of arms 320, 322, and the blocking member 316. The turbine 314 is rotatably mounted via the shaft 318 within the inner section 301 of the housing 302, which partially forms the chamber 304, along with the lower section 305 of the housing 302. Like the turbine 214 in the OPEP device 200, the turbine 314 is configured to rotate in response to a flow of air through the chamber inlet 306, and could have as few as one vane, or many more vanes, the size and shape of which may vary. Each of the pair of arms 320, 322 (also shown in FIG. 16) are fixed to the shaft 318 such that rotation of the turbine 314 and the shaft 318 results in rotation of the arms 320, 322.

[0059] The blocking segment 316 is mounted to the inner section 301 of the housing 302 about a pair of hinges 328, 330, such that the blocking segment 316 may rotate relative to the chamber outlet 308 between a closed position, as shown in FIG. 17, where the flow of air through the chamber outlet 308 is restricted, and an open position, as shown in FIG. 18, where the flow of air through the chamber outlet 308 is less restricted. The blocking member 316 includes a pair of contact surfaces 332, 334 (also shown in FIG. 16) configured to periodically engage the pair of arms 320, 322 as the pair of arms 320, 322 rotate with the turbine 314 and the shaft 318, thereby moving the blocking member 316 from an open position to a closed position. The blocking member 3 6 also has a center of mass offset from the pair of hinges 328, 330, or the axis of rotation, such that when the contact surfaces 332, 334 are not engaged with the pair of arms 320, 322, the blocking member 316 moves to an open position, where the contact surfaces 332, 334 may engage a stop 336.

[0060] The operation of the OPEP device 300 will now be described with reference to the illustration shown in FIGS. 17-18. In FIG. 18, the flow of air through the device 300 is illustrated by a dashed line. However, it should be appreciated that the dashed line is exemplary and provided for purposes of illustration. The actual flow air through the device 300 may traverse any number of flow paths.

[0061] In general, administration of OPEP therapy using the OPEP device 300 begins with the blocking member 316 in an open position, as shown in FIG. 18. As a user exhales in to the mouthpiece 312, exhaled air travels through the housing 302 and enters the chamber 304 through the chamber inlet 306. In response to the flow of air through the chamber inlet 306, the turbine 314 begins to rotate, and exhaled air traverses the chamber 304, exiting the chamber 304 through the chamber outlet 308. Once exhaled air exits the chamber 304, it may travel through the housing 302 and exit the device 300 through the vent 338.

[0062] As a user continues to exhale, and the turbine 314 continues to rotate, the shaft 3 8 rotates, causing the pair of arms 320, 322 to also rotate. As the pair of arms 320, 322 rotate, they periodically engage the contact surfaces 332, 334 on the blocking member 316, as shown in FIG. 17, causing the blocking member 316 to rotate about the pair of hinges 328, 330 from an open position, shown in FIG. 18, to a closed position, shown in FIG. 17. As the blocking member 316 is moved from an open to a closed position, the air flowing through the chamber 304 is restricted from exiting the chamber 304 through the chamber outlet 308, thereby causing the pressure in the chamber 304 and the mouthpiece 312 to increase. As a user continues to exhale, and the turbine 314 continues to rotate, the pair of arms 320, 322 disengage the contact surfaces 332, 334, and the blocking member 316 returns to an open position, allowing the air in the chamber 304 to exit the chamber 304 through the chamber outlet 308, resulting in a decrease in pressure in the chamber 304 and the mouthpiece 312. During a period of exhalation, the blocking member 316 moves repeatedly between an open position and a closed position, causing the pressure in the device 300 to oscillate between a lower pressure and a higher pressure, which is in turn transmitted to the user's airways, thereby administering OPEP therapy.

[0063] Finally, as best seen in FIG. 15-16, the OPEP device 300 is equipped with an inhalation portal 324 having a one-way vale 326, which is shown separately in FIG. 19. The one-way valve 326 includes a plurality of tabs or flaps 327 which are configured to open during a period of inhalation, thereby allowing air to travel through the inhalation port 324 and the one-way valve 326, and close during a period of exhalation, thereby directing the flow of exhaled air through the chamber inlet 306. In this way, a user may exhale into the OPEP device 300 for the administration of OPEP therapy, as described above, and also inhale air surrounding the OPEP device 300 through the inhalation portal 324. Alternatively, the OPEP device 300 may be used in combination with a nebulizer for the combined administration of OPEP and aerosol therapies. Any of a number of commercially available nebulizers may be connected to the OPEP device 300 via the inhalation portal 324. One suitable nebulizer is the AeroEclipse® II breath actuated nebulizer available from Trudell Medical International of London, Canada. Descriptions of suitable nebulizers may also be found, for example, in U.S. Patent No. 5,823,179, the entirety of which is hereby incorporated by reference herein. In this way, a user may exhale into the OPEP device 300 for the administration of OPEP therapy, as described above, and also inhale an aerosolized medicament from an attached nebulizer through the one-way valve 324 and the inhalation portal 324. While the inhalation port 324 is shown in connection with the OPEP device 300, it should be appreciated that the OPEP device 100 and the OPEP device 200 could also include an inhalation port and one way-valve configured to operate as described above.

[0064] Although the description of the embodiments described above refer to the administration of OPEP therapy on exhalation, it should be appreciated that such embodiments are also configurable for the administration of oscillating pressure therapy upon exhalation only, inhalation only, or both exhalation and inhalation. Accordingly, the terms "oscillating positive respiratory pressure" and "oscillating positive expiratory pressure," or ΌΡΕΡ," may be used interchangeably. Similarly, the term "respiratory" may refer to inhalation, exhalation, or both inhalation and exhalation. Use of any such term should not be construed as a limitation to only inhalation or only exhalation.

[0065] The foregoing description of the inventions has been presented for purposes of illustration and description, and is not intended to be exhaustive or to limit the inventions to the precise forms disclosed. It will be apparent to those skilled in the art that the present inventions are susceptible of many variations and modifications coming within the scope of the following claims.