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Title:
OSTEOBLAST AND METHOD FOR PREPARING SAME
Document Type and Number:
WIPO Patent Application WO/2015/012377
Kind Code:
A1
Abstract:
 The present invention relates to: a method for preparing an osteoblast from a somatic cell by introducing a bone-related gene or an expression product thereof and a reprogramming-related gene or an expression product thereof to a somatic cell of a mammal, or introducing a reprogramming-related gene or an expression product thereof independently to a somatic cell of a mammal, the method for preparing an osteoblast in which the bone-related gene is at least one gene selected from the group consisting of Runx2 (R), Osterix (O), and Dlx5 (D), and the reprogramming-related gene is at least one gene selected from the group consisting of the Oct family, c-Myc (M), L-Myc (L), the Klf family, Lin-28, and Sox2; and an osteoblast prepared by the abovementioned method.

Inventors:
YAMAMOTO KENTA (JP)
KISHIDA TSUNAO (JP)
YAMAMOTO TOSHIRO (JP)
MAZDA OSAM (JP)
Application Number:
PCT/JP2014/069628
Publication Date:
January 29, 2015
Filing Date:
July 24, 2014
Export Citation:
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Assignee:
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
International Classes:
C12N15/09; C12N5/10; A61L27/00; A61P19/00
Domestic Patent References:
WO2010098419A12010-09-02
Other References:
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See also references of EP 3026112A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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