Title:
OSTEOCLAST DIFFERENTIATION INHIBITOR CONTAINING UROLITHIN
Document Type and Number:
WIPO Patent Application WO/2019/163437
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an effective and highly safe osteoclast differentiation inhibitor and a food or beverage, a medicine, a supplement, and a cosmetic exhibiting an osteoclast differentiation-inhibiting effect. The problem is solved by an osteoclast differentiation inhibitor containing an urolithin.
Inventors:
KOBATA KENJI (JP)
NAKATANI SACHIE (JP)
KUDOH MASATAKE (JP)
NAKATANI SACHIE (JP)
KUDOH MASATAKE (JP)
Application Number:
PCT/JP2019/002886
Publication Date:
August 29, 2019
Filing Date:
January 29, 2019
Export Citation:
Assignee:
DAICEL CORP (JP)
International Classes:
A61K31/37; A23L33/10; A61P19/08; A61P19/10; A61P43/00
Foreign References:
| JP2017160134A | 2017-09-14 | |||
| JP2017210444A | 2017-11-30 | |||
| JP2017210445A | 2017-11-30 | |||
| JP2014501764A | 2014-01-23 | |||
| JP2017513949A | 2017-06-01 | |||
| US20130324595A1 | 2013-12-05 | |||
| JP2014501764A | 2014-01-23 | |||
| JP2015523362A | 2015-08-13 |
Other References:
OKAMOTO JUNKO: "Regarding pomegranate", NEW FOOD INDUSTRY, vol. 46, no. 6, 2004, pages 1 - 13, XP009523505, ISSN: 0547-0277
MÉLANIE SPILMONT , LAURENT LÉOTOING , MARIE-JEANNE DAVICCO, PATRICE LEBECQUE , ELISABETH MIOT-NOIRAULT , PAUL PILET , LAURENT RIOS: "Pomegranate Peel Extract Prevents Bone Loss in a Preclinical Model of Osteoporosis and Stimulates Osteoblastic Differentiation in Vitro", NUTRIENTS, vol. 7, no. 11, 13 November 2015 (2015-11-13), pages 9265 - 9284, XP055631527, DOI: 10.3390/nu7115465
HORIMOTO, YASUHIRO ET AL.: "Effects of urolithin on differentiation of osteoclast of bone marrow-derived hematopoietic stem cells", LECTURE ABSTRACTS OF THE 72TH CONFERENCE OF JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE, 27 April 2018 (2018-04-27), pages 317, XP009523579
See also references of EP 3756664A4
DENTAL MATERIALS J., vol. 29, 2010, pages 403 - 10
INT. J. MOL. SCI., vol. 15, 2014, pages 18840 - 55
INT. J. SYST. EVOL. MICROBIOL., vol. 64, 2014, pages 2346 - 2352
J. AGRIC. FOOD CHEM., vol. 56, no. 2, 2008, pages 393 - 400
MOL. NUTR. FOOD RES., vol. 58, 2014, pages 1199 - 1211
BIOSCI. BIOTECHNOL. BIOCHEM., vol. 76, no. 2, 2012, pages 395 - 399
J. AGRIC. FOOD CHEM., vol. 60, no. 36, 2012, pages 8866 - 8876
MOL. NUTR. FOOD RES., vol. 55, 2011, pages S35 - S43
FOOD FUNCT., vol. 5, no. 8, 2014, pages 1779 - 1784
MÉLANIE SPILMONT , LAURENT LÉOTOING , MARIE-JEANNE DAVICCO, PATRICE LEBECQUE , ELISABETH MIOT-NOIRAULT , PAUL PILET , LAURENT RIOS: "Pomegranate Peel Extract Prevents Bone Loss in a Preclinical Model of Osteoporosis and Stimulates Osteoblastic Differentiation in Vitro", NUTRIENTS, vol. 7, no. 11, 13 November 2015 (2015-11-13), pages 9265 - 9284, XP055631527, DOI: 10.3390/nu7115465
HORIMOTO, YASUHIRO ET AL.: "Effects of urolithin on differentiation of osteoclast of bone marrow-derived hematopoietic stem cells", LECTURE ABSTRACTS OF THE 72TH CONFERENCE OF JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE, 27 April 2018 (2018-04-27), pages 317, XP009523579
See also references of EP 3756664A4
DENTAL MATERIALS J., vol. 29, 2010, pages 403 - 10
INT. J. MOL. SCI., vol. 15, 2014, pages 18840 - 55
INT. J. SYST. EVOL. MICROBIOL., vol. 64, 2014, pages 2346 - 2352
J. AGRIC. FOOD CHEM., vol. 56, no. 2, 2008, pages 393 - 400
MOL. NUTR. FOOD RES., vol. 58, 2014, pages 1199 - 1211
BIOSCI. BIOTECHNOL. BIOCHEM., vol. 76, no. 2, 2012, pages 395 - 399
J. AGRIC. FOOD CHEM., vol. 60, no. 36, 2012, pages 8866 - 8876
MOL. NUTR. FOOD RES., vol. 55, 2011, pages S35 - S43
FOOD FUNCT., vol. 5, no. 8, 2014, pages 1779 - 1784
Attorney, Agent or Firm:
NIWA, Takeshi et al. (JP)
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