Title:
OVARY-TARGETING POLYPEPTIDE, AND DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/213141
Kind Code:
A1
Abstract:
Provided are an ovary-targeting polypeptide, a derivative of the polypeptide, and use of the polypeptide in the preparation of a drug or reagent for treating ovarian related reproductive diseases and preventing and treating in-vivo or in-vitro aging of oocytes. The diseases comprise menstrual cycle disorder, polycystic ovary syndrome, androgenic phenotype, hair loss, abnormal metabolism, ovarian insufficiency, premature ovarian failure, ovulation failure, abnormal glucose metabolism, and abnormal lipid metabolism, preferably, hyperglycemia and insulin resistance. In addition, the polypeptide is expected to prolong the preservation time and improve the preservation quality of oocytes or fertilized eggs in the field of assisted reproduction.
Inventors:
ZHANG JIAN (CN)
YANG YALI (CN)
ZHAO HUASHAN (CN)
REN PEIGEN (CN)
GE LEI (CN)
ZHU WEN (CN)
XIAO TIANXIA (CN)
LI MENGXIA (CN)
YANG YALI (CN)
ZHAO HUASHAN (CN)
REN PEIGEN (CN)
GE LEI (CN)
ZHU WEN (CN)
XIAO TIANXIA (CN)
LI MENGXIA (CN)
Application Number:
PCT/CN2023/081313
Publication Date:
November 09, 2023
Filing Date:
March 14, 2023
Export Citation:
Assignee:
SHENZHEN INST OF ADV TECH CAS (CN)
International Classes:
C07K7/08; A61K38/10; A61K47/64; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P15/00; C07K16/18; C12N15/12
Foreign References:
| CN114288414A | 2022-04-08 | |||
| CN106892975A | 2017-06-27 | |||
| CN107011427A | 2017-08-04 | |||
| CN114306630A | 2022-04-12 | |||
| CN109957007A | 2019-07-02 |
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (CN)
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