Title:
OXATHIAZINE AND DITHIINE OXIDES AS INHIBITORS OF SULFHYDRYL-DEPENDENT BIOMOLECULES
Document Type and Number:
WIPO Patent Application WO/2012/024083
Kind Code:
A9
Abstract:
Novel derivatives of dihydro-l,4,2-oxathiazine and dihydro-l,4-dithiine oxides, more particularly, novel derivatives of dihydro-l,4,2-oxathiazine and dmydro-l,4-dithiine oxides that target cysteine residues of biomolecules of pharmacological importance are provided as pharmaceutically useful compounds, for example, as anticancer, antiinfectious, antigastric acid secretion, antiosteoporosic, and antiinflammatory agents.
Inventors:
CHEE GAIK-LEAN (CA)
BROUWER WALTER G (CA)
OSIKA EWA (CA)
HASINOFF BRIAN B (CA)
BREWER A DAVID (CA)
BROUWER WALTER G (CA)
OSIKA EWA (CA)
HASINOFF BRIAN B (CA)
BREWER A DAVID (CA)
Application Number:
PCT/US2011/046355
Publication Date:
October 04, 2012
Filing Date:
August 03, 2011
Export Citation:
Assignee:
CHEMTURA CORP (US)
UNIV MANITOBA (CA)
CHEE GAIK-LEAN (CA)
BROUWER WALTER G (CA)
OSIKA EWA (CA)
HASINOFF BRIAN B (CA)
BREWER A DAVID (CA)
UNIV MANITOBA (CA)
CHEE GAIK-LEAN (CA)
BROUWER WALTER G (CA)
OSIKA EWA (CA)
HASINOFF BRIAN B (CA)
BREWER A DAVID (CA)
International Classes:
C07D291/06; A61K31/385; A61K31/54; A61P35/00; C07D339/08
Attorney, Agent or Firm:
VILLAMIZAR, JoAnn (199 Benson RoadMiddlebury, CT, US)
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