Title:
OXA(THIA)ZOLIDINE DERIVATIVE AND ANTI-INFLAMMATORY DRUG
Document Type and Number:
WIPO Patent Application WO/2001/072723
Kind Code:
A1
Abstract:
A medicinal composition characterized by containing as the active ingredient either a compound represented by the general formula (1) or a pharmacologically acceptable composite thereof (wherein X represents oxygen or sulfur; R�1? represents hydrogen, C�1-4? alkyl, etc.; R�2? represents, e.g., phenyl optionally substituted by A�1?; R�3? represents, e.g., hydrogen, C�1-4? alkyl optionally substituted by A�2?, or a group represented by the formula (I) or (II) and R represents oxygen, sulfur, or the formula (N-G), in particular, an inhibitor for phospholipase A(2) activity; a use of the composition; and a compound represented by the general formula (1-1)(wherein X, R�1?, R�2?, R�3?, and G�1? are the same as defined in the description).
Inventors:
TAKAGI MASAE (JP)
ISHIMITSU KEIICHI (JP)
NISHIBE TADAYUKI (JP)
ISHIMITSU KEIICHI (JP)
NISHIBE TADAYUKI (JP)
Application Number:
PCT/JP2001/002481
Publication Date:
October 04, 2001
Filing Date:
March 27, 2001
Export Citation:
Assignee:
NIPPON SODA CO (JP)
TAKAGI MASAE (JP)
ISHIMITSU KEIICHI (JP)
NISHIBE TADAYUKI (JP)
TAKAGI MASAE (JP)
ISHIMITSU KEIICHI (JP)
NISHIBE TADAYUKI (JP)
International Classes:
A61K31/421; A61K31/422; A61K31/426; A61K31/427; A61K31/439; A61K31/4439; A61K31/454; A61K31/4709; A61K31/496; A61K31/506; A61K31/537; A61K31/5377; A61K31/54; A61P1/04; A61P1/16; A61P9/00; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/16; A61P29/00; A61P37/08; A61P43/00; C07D263/16; C07D263/26; C07D263/28; C07D277/14; C07D277/16; C07D277/18; C07D409/12; C07D413/04; C07D413/06; C07D413/10; C07D413/12; C07D417/04; C07D417/06; C07D417/12; C07D417/14; (IPC1-7): C07D263/28; C07D277/18; C07D277/14; C07D277/16; C07D263/26; C07D263/16; C07D413/06; C07D413/12; C07D413/10; C07D417/06; C07D417/04; C07D417/12; C07D413/04; A61K31/426; A61K31/421; A61K31/439; A61K31/427; A61K31/422; A61K31/506; A61K31/4709; A61K31/454; A61K31/496; A61K31/537; A61K31/54; A61P43/00; A61P29/00; A61P37/08; A61P11/06; A61P27/16; A61P11/00; A61P1/04; A61P9/10; A61P9/00; A61P1/16; A61P13/12; A61P25/00; A61P19/02; A61P17/00; A61P17/06; A61P9/02
Domestic Patent References:
| WO2000042031A2 | 2000-07-20 | |||
| WO1982004436A1 | 1982-12-23 | |||
| WO1997005135A1 | 1997-02-13 |
Other References:
TOMINAGA Y. ET AL., TETRAHEDRON LETT., vol. 32, no. 42, 1991, pages 5987 - 5990, XP002942966
See also references of EP 1277743A4
See also references of EP 1277743A4
Attorney, Agent or Firm:
Tokai, Yusaku c/o Nippon Soda Co. (Ltd. 2-1 Ohtemachi 2-chome Chiyoda-ku, Tokyo, JP)
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