Title:
OXAZOLIDINONE AND OXAZINANONE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2015/152368
Kind Code:
A1
Abstract:
Provided is a novel compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The compound or pharmaceutically acceptable salt thereof exhibits orexin (OX) receptor antagonistic action, and thus is useful for the treatment or prevention of medical conditions such as sleep disorders, depression, anxiety disorders, panic disorders, schizophrenia, drug dependence, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorders, headaches, migraines, pain, digestive organ diseases, epilepsy, inflammation, immunological diseases, endocrine-related diseases, and hypertension.
Inventors:
SUZUKI RYO (JP)
MATSUDA YOHEI (JP)
MATSUDA YOHEI (JP)
Application Number:
PCT/JP2015/060450
Publication Date:
October 08, 2015
Filing Date:
April 02, 2015
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
International Classes:
C07D498/10; A61K31/4709; A61K31/498; A61K31/506; A61K31/537; A61P1/00; A61P5/00; A61P9/12; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/36; A61P29/00; A61P37/02; A61P43/00; C07D519/00
Domestic Patent References:
| WO2012101487A1 | 2012-08-02 |
Foreign References:
| JP2013515033A | 2013-05-02 | |||
| JP2013540792A | 2013-11-07 |
Other References:
MASAKATSU NOZAKI ET AL., MEDICINAL CHEMISTRY, 1 July 1995 (1995-07-01), pages 98 - 99
BRUNCKO,M. ET AL.: "Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL", JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, no. 4, 26 January 2007 (2007-01-26), pages 641 - 662, XP002661692
BRUNCKO,M. ET AL.: "Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL", JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, no. 4, 26 January 2007 (2007-01-26), pages 641 - 662, XP002661692
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
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