OXO-SUBSTITUTED COMPOUND - SUMITOMO DAINIPPON PHARMA CO LTD

Title:

OXO-SUBSTITUTED COMPOUND

Document Type and Number:

WIPO Patent Application WO/2019/208797

Kind Code:

A1

Abstract:

Provided is a novel compound that has an excellent β-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent β-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a β-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and β-lactam drugs.

Inventors:

KANAI TOSHIO (JP)
KOIKE SACHIKO (JP)
FUKAYA TAKAYUKI (JP)
UESUGI SHUNICHIRO (JP)
MIZUSHIMA SHINGO (JP)
SUDA HITOSHI (JP)
MIZUKAMI YUKI (JP)
IKUMA YOHEI (JP)
SUNAZUKA TOSHIAKI (JP)
NOGUCHI YOSHIHIKO (JP)

Application Number:

PCT/JP2019/018011

Publication Date:

October 31, 2019

Filing Date:

April 26, 2019

Export Citation:

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Assignee:

SUMITOMO DAINIPPON PHARMA CO LTD (JP)
THE KITASATO INST (JP)

International Classes:

C07F5/02; A61K31/407; A61K31/427; A61K31/69; A61K45/00; A61P1/02; A61P1/16; A61P11/00; A61P11/02; A61P11/04; A61P13/02; A61P15/08; A61P17/02; A61P19/02; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P37/08; A61P43/00

Domestic Patent References:

WO2015179308A1	2015-11-26
WO2016149393A1	2016-09-22
WO2014110442A1	2014-07-17
WO2016003929A1	2016-01-07
WO2014089365A1	2014-06-12

Other References: