Title:
P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/085916
Kind Code:
A1
Abstract:
A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drug for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.
Inventors:
ZHAO YANPING (CN)
WANG HONGJUN (CN)
LI GONG (CN)
LI XIANG (CN)
JIANG YUANYUAN (CN)
LIU KAI (CN)
WANG YEMING (CN)
ZHOU LIYING (CN)
LIU YANAN (CN)
SHAO NING (CN)
XIAO FENGPING (CN)
WANG HONGJUN (CN)
LI GONG (CN)
LI XIANG (CN)
JIANG YUANYUAN (CN)
LIU KAI (CN)
WANG YEMING (CN)
ZHOU LIYING (CN)
LIU YANAN (CN)
SHAO NING (CN)
XIAO FENGPING (CN)
Application Number:
PCT/CN2018/112829
Publication Date:
May 09, 2019
Filing Date:
October 31, 2018
Export Citation:
Assignee:
BEIJING TIDE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/12; A61K31/506; C07D239/48; C07D401/06
Domestic Patent References:
| WO2017165255A1 | 2017-09-28 |
Foreign References:
| CN1930135A | 2007-03-14 |
Other References:
KOMPIS, I. ET AL.: "2, 4-Diamino-5-(Pyridylmethyl)-Pyrimidine Als Potentielle Chemotherapeutica(Abstract 237)", CHEMISCHER INFORMATIONSDIENS T, vol. 9, no. 14, 4 April 1978 (1978-04-04), XP055683200, ISSN: 1522-2667
G. W. H. CHEESEMANE. S. G. WERSTIUK: "Pro-drugs as Novel Delivery Systems", vol. 14, 1985, ACS SYMPOSIUM SERIES, pages: 390 - 392
T.W. GREENEP.G.M. WUTS: "Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS
REMINGTON'S PHARMACEUTICAL SCIENCES, 1990
See also references of EP 3712144A4
G. W. H. CHEESEMANE. S. G. WERSTIUK: "Pro-drugs as Novel Delivery Systems", vol. 14, 1985, ACS SYMPOSIUM SERIES, pages: 390 - 392
T.W. GREENEP.G.M. WUTS: "Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS
REMINGTON'S PHARMACEUTICAL SCIENCES, 1990
See also references of EP 3712144A4
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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