Title:
PROCESS FOR PRODUCING tert-LEUCINE
Document Type and Number:
WIPO Patent Application WO/2003/074470
Kind Code:
A1
Abstract:
A process for producing tert-leucine characterized by reacting tert-leucine with a substituted benzenesulfonic acid represented by the following general formula (1): (1) (wherein R1 and R2 each independently represents hydrogen, alkyl, or halogeno, provided that at least one of R1 and R2 is not hydrogen) in a solvent to obtain a tert-leucine/substituted benzesulfonic acid salt represented by the following general formula (2): (2) (wherein R1 and R2 are the same as defined above), separating the salt by crystallization, and then decomposing the salt. In this tert-leucine production process, a tert-leucine salt sparingly soluble in a solvent is formed and then crystallized. Thus, the tert-leucine can be efficiently recovered from the solvent.
More Like This:
Inventors:
NAGASHIMA KAZUTAKA (JP)
TAKEMOTO TADASHI (JP)
TAKEMOTO TADASHI (JP)
Application Number:
PCT/JP2003/002310
Publication Date:
September 12, 2003
Filing Date:
February 28, 2003
Export Citation:
Assignee:
AJINOMOTO KK (JP)
NAGASHIMA KAZUTAKA (JP)
TAKEMOTO TADASHI (JP)
NAGASHIMA KAZUTAKA (JP)
TAKEMOTO TADASHI (JP)
International Classes:
C07C227/42; C07C229/08; C07C303/32; C07C309/30; C07C309/39; (IPC1-7): C07C229/08; C07C227/42
Foreign References:
EP0861826A1 | 1998-09-02 | |||
JPS523016A | 1977-01-11 | |||
JPS4857914A | 1973-08-14 | |||
EP0748791A2 | 1996-12-18 | |||
JPH05271169A | 1993-10-19 |
Other References:
See also references of EP 1498410A4
Attorney, Agent or Firm:
Takashima, Hajime (2-14 Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka, JP)
Download PDF: