Title:
PROCESS FOR REDUCING $G(a)-AMINO KETONES
Document Type and Number:
WIPO Patent Application WO/1998/055452
Kind Code:
A1
Abstract:
A process for stereoselectively reducing $g(a)-amino haloketone derivatives under mild conditions, which comprises reacting an $g(a)-amino haloketone derivative of general formula (1) with a compound prepared from an organoaluminum compound of general formula (4), a sulfonic acid derivative of the general formula (5): R?6�SO�3?H, and an alcohol compound of the general formula (6): R?7�OH to yield an $g(a)-amino alcohol derivative of general formula (7).
Inventors:
MATSUO KAZUHIKO (JP)
MATSUMOTO SHINGO (JP)
INOUE KENJI (JP)
MATSUMOTO SHINGO (JP)
INOUE KENJI (JP)
Application Number:
PCT/JP1998/002444
Publication Date:
December 10, 1998
Filing Date:
June 03, 1998
Export Citation:
Assignee:
KANEKA CORP (JP)
MATSUO KAZUHIKO (JP)
MATSUMOTO SHINGO (JP)
INOUE KENJI (JP)
MATSUO KAZUHIKO (JP)
MATSUMOTO SHINGO (JP)
INOUE KENJI (JP)
International Classes:
C07C269/06; C07C271/16; C07C271/22; (IPC1-7): C07C269/06; C07C271/16; C07C323/44; C07C271/22; C07B41/02
Domestic Patent References:
| WO1998011057A1 | 1998-03-19 | |||
| WO1997028105A1 | 1997-08-07 |
Foreign References:
| JPH0525107A | 1993-02-02 | |||
| JPH07165678A | 1995-06-27 | |||
| JPH051000A | 1993-01-08 | |||
| JPS50137911A | 1975-11-01 | |||
| JPS63297333A | 1988-12-05 | |||
| JPS632935A | 1988-01-07 | |||
| JPS62286938A | 1987-12-12 | |||
| JPS54154739A | 1979-12-06 | |||
| JPH08143517A | 1996-06-04 | |||
| JPH0812629A | 1996-01-16 | |||
| US5475138A | 1995-12-12 | |||
| JPH0899947A | 1996-04-16 | |||
| JPH08198837A | 1996-08-06 | |||
| JPH029849A | 1990-01-12 | |||
| JPH09194444A | 1997-07-29 |
Other References:
MUELLER H K, ET AL.: "ERGEBNISSE DER REDUKTION VON RACEMISCHEN ALPHA-ARYLAMINOPROPIOPHENON-DERIVATEN MIT ALUMINIUM-ISOPROPYLAT", JOURNAL FUER PRAKTISCHE CHEMIE (LEIPZIG), vol. 315, no. 04, 1 January 1973 (1973-01-01), pages 611 - 619, XP002911179, ISSN: 0021-8383, DOI: 10.1002/prac.19733150405
Attorney, Agent or Firm:
Yasutomi, Yasuo (14-22 Nishinakajima 5-chome, Yodogawa-k, Osaka-shi Osaka, JP)
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