PRODUCTION OF alpha-(3-BENZOYLPHENYL)PROPIONIC ACID DERIVATIVE

WIPO Patent Application WO/1990/010614

A1

This invention provides a method of producing highly pure alpha-(3-benzoylphenyl)propionic acid derivatives, which are pharmaceuticals per se or which can easily afford the same, from readily available 3-ethylbenzophenone in a very simplified manner efficiently and economically. The method comprises dehydrogenating 3-ethylbenzophenone in vapor phase in the presence of an inert gas and carbonylating the formed 3-ethenylbenzophenone in the presence of a carbonylation catalyst comprising a transition metal complex.

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SHIMIZU ISOO (JP)
MATSUMURA YASUO (JP)
INOMATA YOSHIHISA (JP)

PCT/JP1990/000288

September 20, 1990

March 06, 1990

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NIPPON PETROCHEMICALS CO LTD (JP)

B01J31/16; C07B61/00; C07C45/50; C07C45/65; C07C49/782; C07C49/796; C07C49/86; C07C51/14; C07C59/84; C07C67/38; C07C69/738; C07C69/76; (IPC1-7): C07C45/65; C07C49/796; C07C51/14; C07C59/84; C07C67/38; C07C69/738

JPS6413052A	1989-01-17
JPS63290842A	1988-11-28
JPS5626833A	1981-03-16
JPS5318533A	1978-02-20

See also references of EP 0422235A1

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