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Title:
PROTEIN BINDING TO NE-dlg
Document Type and Number:
WIPO Patent Application WO/1999/043702
Kind Code:
A1
Abstract:
A protein (named 'Nedasin') which binds to NE-dlg, shows no homology with any known mammalian protein and has a molecular weight of 51 kD; polynucleotides encoding the above Nedasin or its mutants; antisense polynucleotides comprising the complementary base sequences of the base sequences of the above polynucleotides; and an antibody recognizing the above-mentioned Nedasin or its mutants.

Inventors:
KISHIMOTO TOSHIHIKO (JP)
NIWA SHIN-ICHIRO (JP)
KUWAHARA HIROAKI (JP)
SAYA HIDEYUKI (JP)
Application Number:
PCT/JP1998/003740
Publication Date:
September 02, 1999
Filing Date:
August 24, 1998
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Assignee:
SUMITOMO ELECTRIC INDUSTRIES (JP)
KISHIMOTO TOSHIHIKO (JP)
NIWA SHIN ICHIRO (JP)
KUWAHARA HIROAKI (JP)
SAYA HIDEYUKI (JP)
International Classes:
C12N15/09; C07K14/47; C07K16/18; C12N1/21; C12N15/00; C12N15/12; C12P21/02; C12R1/19; C12R1/91; (IPC1-7): C07K14/47; C07K16/18; C12N15/12; C12Q1/68
Other References:
ONCOGENE, Vol. 14, No. 20, (1997), MAKINO K. et al., "Cloning and Characterization of NE-dlg: A Novel Homolog of the Drosophila Disc Large (dlg) Tumor Suppressor Protein Interacts with the APC Protein", p. 2425-2433.
Attorney, Agent or Firm:
Hasegawa, Yoshiki (6th floor 13-10, Kyobashi 2-chome Chuo-ku Tokyo, JP)
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