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Title:
PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/194831
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a compound having an excellent CDK4/6 inhibiting activity. The present invention is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof.

Inventors:
MIZUNO TSUYOSHI (JP)
SHIMADA TOMOHIRO (JP)
UNOKI GEN (JP)
EBISAWA MASARU (JP)
TAKEUCHI SUSUMU (JP)
MINAMIZONO KUNIO (JP)
SASAKI KOSUKE (JP)
YOKOSAKA TAKUYA (JP)
IGARASHI JUNJI (JP)
MARUYAMA AKINOBU (JP)
TAKAHASHI HIROSHI (JP)
HORIE KYOHEI (JP)
SAKAI YURI (JP)
Application Number:
PCT/JP2016/065770
Publication Date:
December 08, 2016
Filing Date:
May 27, 2016
Export Citation:
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Assignee:
TEIJIN PHARMA LTD (JP)
International Classes:
C07D471/04; A61K31/519; A61K31/5377; A61K31/5386; A61K31/541; A61K31/55; A61K31/551; A61K31/553; A61P9/10; A61P11/00; A61P19/02; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07D519/00
Domestic Patent References:
WO2014037750A12014-03-13
Foreign References:
JP2005519909A2005-07-07
JP2007530425A2007-11-01
Other References:
INNOCENTI, P. ET AL.: "Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, 21 January 2015 (2015-01-21), pages 893 - 904, XP055332115, ISSN: 1477-0520
See also references of EP 3305785A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Aoki 篤 (JP)
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