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Title:
PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2015/093567
Kind Code:
A1
Abstract:
The present invention is a pain-related compound, a medicinal composition, and uses thereof. One or multiple embodiments are a compound represented by formula (I), a prodrug thereof, or a pharmaceutically permissible salt thereof.

Inventors:
HAGIWARA MASATOSHI (JP)
TOYOMOTO MASAYASU (JP)
HOSOYA TAKAMITSU (JP)
YOSHIDA SUGURU (JP)
KURIHARA TAKASHI (JP)
Application Number:
PCT/JP2014/083569
Publication Date:
June 25, 2015
Filing Date:
December 18, 2014
Export Citation:
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Assignee:
UNIV KYOTO (JP)
NAT UNIV CORP TOKYO MED & DENT (JP)
UNIV KAGOSHIMA (JP)
International Classes:
C07D277/64; A61K31/428; A61P25/04; A61P29/00
Domestic Patent References:
WO2013168826A12013-11-14
WO2009085226A22009-07-09
WO2010010797A12010-01-28
WO2010010797A12010-01-28
Foreign References:
JPS5089367A1975-07-17
US20080255123A12008-10-16
US20050171026A12005-08-04
JP2004002352A2004-01-08
JP2008539269A2008-11-13
US20050171026A12005-08-04
Other References:
MURAKI M. ET AL.: "Manipulation of Alternative Splicing by a NewlyDeveloped Inhibitor of Clks", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, no. 23, 2004, pages 24246 - 24254, XP055192700
KURIHARA, T. ET AL.: "Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors", MOLECULAR PAIN, vol. 10, pages 17 /1 - 17/13, XP021180976
M. MURAKI ET AL.: "Manipulation of Alternative Splicing by a Newly Developed Inhibitor of Clks", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, 2004, pages 24246 - 24254, XP055192700, DOI: doi:10.1074/jbc.M314298200
Attorney, Agent or Firm:
IKEUCHI SATO & PARTNER PATENT ATTORNEYS (JP)
Patent business corporation Ikeuchi and Sato and partners (JP)
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