Title:
PALBOCICLIB SACCHARINATE CRYSTAL FORM AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/040668
Kind Code:
A1
Abstract:
A Palbociclib saccharinate crystal form and a preparation method therefor. A prepared Palbociclib saccharinate crystal form α has excellent physical and chemical stability, high solubility, and good dissolution, fluidity and bioavailability. The Palbociclib saccharinate crystal form α has mild preparation conditions, simple operations, good process reproducibility, and high purity, so as to achieve controllable industrial production conditions, thereby facilitating large-scale industrialization.
Inventors:
HUANG CUI (CN)
GU HUIKE (CN)
YANG HAILONG (CN)
CHEN HONG (CN)
WANG YING (CN)
GU HUIKE (CN)
YANG HAILONG (CN)
CHEN HONG (CN)
WANG YING (CN)
Application Number:
PCT/CN2022/120451
Publication Date:
February 29, 2024
Filing Date:
September 22, 2022
Export Citation:
Assignee:
CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D471/04; A61K31/519; A61P35/00
Domestic Patent References:
| WO2016090257A1 | 2016-06-09 | |||
| WO2016092442A1 | 2016-06-16 | |||
| WO2017021111A1 | 2017-02-09 |
Foreign References:
| CN106967061A | 2017-07-21 | |||
| CN106317053A | 2017-01-11 |
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