Title:
PANCREATIC FUNCTION ACTIVATING AGENT, ANTI-AGING AGENT, THERAPEUTIC OR PROPHYLACTIC AGENT FOR TYPE-2 DIABETES, MEDICINE, COSMETIC, AND FOOD OR BEVERAGE
Document Type and Number:
WIPO Patent Application WO/2023/218804
Kind Code:
A1
Abstract:
An adipose-derived stem cells exosome and at least one component selected from the group consisting of recombinant leptin, γ-oryzanol, inulin, zinc and vitamin C are contained.
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Inventors:
DAN KATSUAKI (JP)
QI XIA (CN)
QI XIA (CN)
Application Number:
PCT/JP2023/014018
Publication Date:
November 16, 2023
Filing Date:
April 05, 2023
Export Citation:
Assignee:
DAN KATSUAKI (JP)
QI XIA (CN)
QI XIA (CN)
International Classes:
A61K35/12; A23L33/10; A23L33/11; A23L33/15; A23L33/16; A23L33/17; A23L33/21; A61K8/27; A61K8/60; A61K8/63; A61K8/64; A61K8/67; A61K8/98; A61K31/375; A61K31/575; A61K31/733; A61K33/30; A61K35/28; A61K38/22; A61P1/18; A61P3/10; A61P43/00; A61Q19/08
Foreign References:
| JP2020519668A | 2020-07-02 | |||
| JP2021116228A | 2021-08-10 | |||
| JPH05310526A | 1993-11-22 | |||
| JP2004501176A | 2004-01-15 | |||
| JPH05506840A | 1993-10-07 |
Other References:
T. KUSAKABE ; H. TANIOKA ; K. EBIHARA ; M. HIRATA ; L. MIYAMOTO ; F. MIYANAGA ; H. HIGE ; D. AOTANI ; T. FUJISAWA ; H. MASUZAKI ; : "Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and a high-fat diet", DIABETOLOGIA, SPRINGER, BERLIN, DE, vol. 52, no. 4, 24 January 2009 (2009-01-24), Berlin, DE , pages 675 - 683, XP019698533, ISSN: 1432-0428
INA SHIGENOBU, HAMADA AYA, KUMAGAI HITOMI, YAMAGUCHI YUSUKE: "Bioactive Ingredients in Rice (Oryza sativa L.) Function in the Prevention of Type 2 Diabetes", JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, vol. 65, no. Supplement, 11 October 2019 (2019-10-11), pages S113 - S116, XP093106798, ISSN: 0301-4800, DOI: 10.3177/jnsv.65.S113
ZHANG WENYUE, TANG YAO, HUANG JUAN, YANG YIXUAN, YANG QINBING, HU HUAIDONG: "Efficacy of inulin supplementation in improving insulin control, HbA1c and HOMA IR in patients with type 2 diabetes: a systematic review and meta analysis of randomized controlled trials", JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, vol. 66, no. 3, 6 March 2020 (2020-03-06), pages 176 - 183, XP093106801, DOI: 10.3164/jcbn.19103
KOJIMA YOSHITANE, YUTAKA YOSHIKAWA, NAMI IKURA, RIE UEDAI, AKLO ICHIMURA, MATSUML DOE, HLROMU SAKURAI: "Improvement of Glucose Tolerance by Vitamin C/Zinc(II) Complexes", BITAMIN = VITAMINS, NIPPON BITAMIN GAKKAI, JP, vol. 77, no. 10, 1 October 2003 (2003-10-01), JP , pages 571 - 576, XP093106807, ISSN: 0006-386X
LIAO, N. et al. Adipose tissue-derived stem cells ameliorate hyperglycemia, insulin resistance and liver fibrosis in the type 2 diabetic rats. Stem Cell Research & Therapy. 2017, vol. 8, no. 1, 286, doi:10.1186/s13287-017-0743-7, ISSN: 1757-6512
INA SHIGENOBU, HAMADA AYA, KUMAGAI HITOMI, YAMAGUCHI YUSUKE: "Bioactive Ingredients in Rice (Oryza sativa L.) Function in the Prevention of Type 2 Diabetes", JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, vol. 65, no. Supplement, 11 October 2019 (2019-10-11), pages S113 - S116, XP093106798, ISSN: 0301-4800, DOI: 10.3177/jnsv.65.S113
ZHANG WENYUE, TANG YAO, HUANG JUAN, YANG YIXUAN, YANG QINBING, HU HUAIDONG: "Efficacy of inulin supplementation in improving insulin control, HbA1c and HOMA IR in patients with type 2 diabetes: a systematic review and meta analysis of randomized controlled trials", JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, vol. 66, no. 3, 6 March 2020 (2020-03-06), pages 176 - 183, XP093106801, DOI: 10.3164/jcbn.19103
KOJIMA YOSHITANE, YUTAKA YOSHIKAWA, NAMI IKURA, RIE UEDAI, AKLO ICHIMURA, MATSUML DOE, HLROMU SAKURAI: "Improvement of Glucose Tolerance by Vitamin C/Zinc(II) Complexes", BITAMIN = VITAMINS, NIPPON BITAMIN GAKKAI, JP, vol. 77, no. 10, 1 October 2003 (2003-10-01), JP , pages 571 - 576, XP093106807, ISSN: 0006-386X
LIAO, N. et al. Adipose tissue-derived stem cells ameliorate hyperglycemia, insulin resistance and liver fibrosis in the type 2 diabetic rats. Stem Cell Research & Therapy. 2017, vol. 8, no. 1, 286, doi:10.1186/s13287-017-0743-7, ISSN: 1757-6512
Attorney, Agent or Firm:
FUJIMOTO Yoshihiro (JP)
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