Title:
PCL PATCH TISSUE REGENERATION SCAFFOLD AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2018/012702
Kind Code:
A1
Abstract:
The present invention relates to a PCL patch tissue regeneration scaffold and a method for manufacturing same and, more particularly, provides a method for manufacturing a PCL patch tissue regeneration scaffold, wherein the method comprises: a step for preparing a solution by adding polycaprolactone (PCL) and an acid to an organic solvent, and then stirring; a step for preparing an electrospinning solution by adding a growth factor to the solution, and then stirring; and a step for collecting nanofibers in a fusiform arrangement in a collector by connecting the prepared electrospinning solution to a syringe pump, and then operating an electrospinning machine. A PCL patch tissue regeneration scaffold according to the present invention may be usefully used for the treatment of acute and chronic tympanic membrane perforation. In particular, the PCL patch tissue regeneration scaffold can reduce the preference given to surgery in treatment methods that rely on surgery to treat chronic tympanic membrane perforation, and enable a high rate of tympanic membrane recovery. Moreover, the PCL and patch tissue regeneration scaffold can be applied to the regeneration and treatment of other damaged tissue, and by mimicking the tissue structure of other parts of the body, enable the development and application of various tissue regeneration scaffolds.
Inventors:
CHOUNG YUN-HOON (KR)
CHUNG JONG HOON (KR)
SEONWOO HOON (KR)
JANG KYOUNG-JE (KR)
SHIN BEOMYONG (KR)
CHUNG JONG HOON (KR)
SEONWOO HOON (KR)
JANG KYOUNG-JE (KR)
SHIN BEOMYONG (KR)
Application Number:
PCT/KR2017/002262
Publication Date:
January 18, 2018
Filing Date:
March 02, 2017
Export Citation:
Assignee:
AJOU UNIV INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR)
International Classes:
A61L27/18; A61F11/00; A61F13/00; A61L27/54; D01D5/00
Domestic Patent References:
| WO2015040554A1 | 2015-03-26 |
Foreign References:
| JP5424561B2 | 2014-02-26 | |||
| KR20080013224A | 2008-02-13 | |||
| KR20150084519A | 2015-07-22 | |||
| KR101636778B1 | 2016-07-06 |
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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