Title:
PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS
Document Type and Number:
WIPO Patent Application WO2000018823
Kind Code:
A3
Abstract:
The present invention relates to macromonomers containing ethylene glycol repeat units, to chemically inert polymers prepared therefrom and to the use of such polymers in solid phase biochemical assays. A macromonomer of polyethylene glycol having repeat units in the range 6-300 and having at least one end terminated by an ether group having formula (I) where m is an integer of 0-10, a is an integer of 1-4, and R is H or alkyl or aryl or arylalkyl; or having formula (II) where m is an integer of 1-10, and R is H or alkyl or aryl or arylalkyl.
Inventors:
MELDAL MORTEN (DK)
BUCHARDT JENS (DK)
RADEMANN JOERG (DK)
BUCHARDT JENS (DK)
RADEMANN JOERG (DK)
Application Number:
PCT/DK1999/000508
Publication Date:
August 17, 2000
Filing Date:
September 28, 1999
Export Citation:
Assignee:
CARLSBERG AS (DK)
MELDAL MORTEN (DK)
BUCHARDT JENS (DK)
RADEMANN JOERG (DK)
MELDAL MORTEN (DK)
BUCHARDT JENS (DK)
RADEMANN JOERG (DK)
International Classes:
A61B1/247; B01D15/08; B01J20/26; B01J20/281; G01N37/00; B01J20/30; C07C231/12; C07C237/12; C07D305/06; C07K1/04; C07K17/08; C08F2/00; C08F2/32; C08F283/06; C08F290/06; C08F299/02; C08G65/22; C08G65/26; C08G65/32; C08G65/329; C08G65/331; C12N11/08; C40B40/02; C40B40/04; C40B40/14; C40B50/06; G01N30/88; (IPC1-7): C08G65/32; C08G65/26; C08F283/06; C07K1/04
Domestic Patent References:
| WO1997042242A1 | 1997-11-13 | |||
| WO1991015952A1 | 1991-10-31 | |||
| WO1999029759A1 | 1999-06-17 |
Foreign References:
| US5352756A | 1994-10-04 | |||
| US5573934A | 1996-11-12 | |||
| US4774356A | 1988-09-27 | |||
| EP0415404A2 | 1991-03-06 |
Other References:
GNANOU ET AL.: "Macromonomer synthesis. New functionalization methods", MAKROMOL. CHEM., vol. 188, 1987, pages 2111 - 2119, XP002126363
CHEMICAL ABSTRACTS, vol. 130, no. 8, 22 February 1999, Columbus, Ohio, US; abstract no. 96182, BUCHARDT, JENS ET AL: "A chemically inert hydrophilic resin for solid phase organic synthesis" XP002126364
CHEMICAL ABSTRACTS, vol. 121, no. 8, 22 August 1994, Columbus, Ohio, US; abstract no. 84500, KAWAGUCHI, SEIGOU ET AL: "Fluorescence Probe Study of Micelle Formation of Poly(ethylene oxide) Macromonomers in Water" XP002126365
CHEMICAL ABSTRACTS, vol. 126, no. 22, 2 June 1997, Columbus, Ohio, US; abstract no. 293659, NOMURA, EIJI ET AL: "Radical Polymerization Kinetics of Poly(ethylene oxide) Macromonomers" XP002126366
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; RADEMANN, JOERG ET AL: "SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase", XP002133382, retrieved from STN Database accession no. 131:129548
CHEMICAL ABSTRACTS, vol. 130, no. 8, 22 February 1999, Columbus, Ohio, US; abstract no. 96182, BUCHARDT, JENS ET AL: "A chemically inert hydrophilic resin for solid phase organic synthesis" XP002126364
CHEMICAL ABSTRACTS, vol. 121, no. 8, 22 August 1994, Columbus, Ohio, US; abstract no. 84500, KAWAGUCHI, SEIGOU ET AL: "Fluorescence Probe Study of Micelle Formation of Poly(ethylene oxide) Macromonomers in Water" XP002126365
CHEMICAL ABSTRACTS, vol. 126, no. 22, 2 June 1997, Columbus, Ohio, US; abstract no. 293659, NOMURA, EIJI ET AL: "Radical Polymerization Kinetics of Poly(ethylene oxide) Macromonomers" XP002126366
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; RADEMANN, JOERG ET AL: "SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase", XP002133382, retrieved from STN Database accession no. 131:129548
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