Title:
PELLET CONTAINING CYSTEINE HYDROCHLORIDE AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/161576
Kind Code:
A1
Abstract:
Disclosed is a pellet using cysteine hydrochloride as a main component, which contains the cysteine hydrochloride and another pharmaceutically acceptable binder, an anti-tack agent, and an optional diluent. For a drug in which the solubility decreases as the pH increases, the prepared cysteine hydrochloride pellet has an improved dissolution rate and other advantages.
Inventors:
LI JIAN (CN)
SHENG XIAOXIA (CN)
SHENG XIAOXIA (CN)
Application Number:
PCT/CN2015/076062
Publication Date:
October 13, 2016
Filing Date:
April 08, 2015
Export Citation:
Assignee:
SOLIPHARMA LLC (CN)
International Classes:
A61K9/16; A61K47/12
Foreign References:
CN101897674A | 2010-12-01 | |||
CN102675174A | 2012-09-19 | |||
JP2003155232A | 2003-05-27 | |||
JP2004269384A | 2004-09-30 | |||
JP2006188473A | 2006-07-20 |
Other References:
CHE, WENSHI ET AL.: "Progress on Pellets Preparation Technology", HEILONGJIANG MEDICINE JOURNAL, vol. 25, no. 5, 31 December 2012 (2012-12-31), pages 693 - 695
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