PEPTIDASE INHIBITORS - ROYALTY SUSAN MARIE

Title:

PEPTIDASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO2006012395

Kind Code:

A3

Abstract:

The present invention relates to a series of novel compounds having the formula (I) wherein: X is NR³ or O; n is 1 or 2; A is a bicyclic carbocycle and R1 and R2 are as described herein. The compounds are useful as DPP-IV inhibitors, such as for the treatment of diabetes.

Inventors:

ROYALTY SUSAN MARIE (US)
BURNS JAMES FORD (US)
SCICINSKI JAN JOZEF (US)
JAGDMANN JR GUNNAR ERIK (US)
FOGLESONG ROBERT JAMES (US)
GRIFFIN KELLEE RENEE (US)
DYAKONOV TATYANA (US)
MIDDLEMISS DAVID (GB)

Application Number:

PCT/US2005/025837

Publication Date:

May 04, 2006

Filing Date:

July 21, 2005

Export Citation:

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Assignee:

ROYALTY SUSAN MARIE (US)
BURNS JAMES FORD (US)
SCICINSKI JAN JOZEF (US)
JAGDMANN JR GUNNAR ERIK (US)
FOGLESONG ROBERT JAMES (US)
GRIFFIN KELLEE RENEE (US)
DYAKONOV TATYANA (US)
MIDDLEMISS DAVID (GB)

International Classes:

A61K31/4025; C07D207/09; C07D207/10

Domestic Patent References:

WO2005021536A2

2005-03-10

Other References: