Title:
PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/015644
Kind Code:
A1
Abstract:
A peptide amide compound shown in general formula (I) and a preparation method and medical use thereof. The compound is used to treat or prevent a disease or condition related to κ-opioid receptor in mammals. (I)
More Like This:
| WO/1997/010262 | PEPTIDE DERIVATIVES |
| WO/2003/064447 | IMMUNE−MODULATING PEPTIDE |
Inventors:
ZHANG CHEN (CN)
HUANG ANBANG (CN)
YE FEI (CN)
HUANG LONGBIN (CN)
HUANG ZHENGGANG (CN)
WANG JIANMIN (CN)
WEI YONGGANG (CN)
YAN PANGKE (CN)
ZHENG WEI (CN)
HUANG ANBANG (CN)
YE FEI (CN)
HUANG LONGBIN (CN)
HUANG ZHENGGANG (CN)
WANG JIANMIN (CN)
WEI YONGGANG (CN)
YAN PANGKE (CN)
ZHENG WEI (CN)
Application Number:
PCT/CN2018/096271
Publication Date:
January 24, 2019
Filing Date:
July 19, 2018
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K5/107; A61K38/07; A61P25/04
Domestic Patent References:
| WO2008057608A2 | 2008-05-15 |
Foreign References:
| CN101627049A | 2010-01-13 | |||
| US20110212882A1 | 2011-09-01 | |||
| US20100075910A1 | 2010-03-25 | |||
| CN101535336A | 2009-09-16 | |||
| CN101454338A | 2009-06-10 | |||
| CN1283201A | 2001-02-07 | |||
| CN101627049A | 2010-01-13 |
Other References:
WOOLD ET AL.: "described the use of K opioid receptor agonists for the treatment of pain sensitization", ANASTHESIA AND ANALGESIA, vol. 77, 1993, pages 362 - 379
WU ET AL.: "proposed K opioid receptor agonists as targets for the prevention and treatment of cardiovascular diseases", CIRCULATION RES, vol. 84, 1999, pages 1388 - 1395
KAUSHIK ET AL.: "described the neuroprotective effects of K opioid receptor agonists", J. POSTGRADUATE MEDICINE, vol. 49, no. 1, 2003, pages 90 - 95
POTTER ET AL.: "described the use of K opioid receptor agonists in ocular disorders and ocular pain", PHARMACOL. EXP. THER, vol. 209, 2004, pages 548 - 553
WIKSTROM ET AL.: "described the use of K agonists in the treatment of uremia and opium-induced pruritus", J. AM. SOC.NEPHROL, vol. 16, 2005, pages 3742 - 3747
BILEVICIUTE-LJUNGAR ET AL.: "evaluated the properties of K opioid receptor agonists for inflammatory diseases such as osteoarthritis and rheumatoid arthritis", RHEUMATOLOGY, vol. 45, 2006, pages 295 - 302
LEMBO: "evaluated the use of K opioid receptor agonists in gastrointestinal diseases", DIGES.DIS., vol. 24, 2006, pages 91 - 98
JOLIVALT ET AL.: "described the role of the K opioid receptor agonist acimadrine in rodent diabetic neuropathy", DIABETOLOGIA, vol. 49, no. 11, 2006, pages 2775 - 2785
See also references of EP 3656782A4
WU ET AL.: "proposed K opioid receptor agonists as targets for the prevention and treatment of cardiovascular diseases", CIRCULATION RES, vol. 84, 1999, pages 1388 - 1395
KAUSHIK ET AL.: "described the neuroprotective effects of K opioid receptor agonists", J. POSTGRADUATE MEDICINE, vol. 49, no. 1, 2003, pages 90 - 95
POTTER ET AL.: "described the use of K opioid receptor agonists in ocular disorders and ocular pain", PHARMACOL. EXP. THER, vol. 209, 2004, pages 548 - 553
WIKSTROM ET AL.: "described the use of K agonists in the treatment of uremia and opium-induced pruritus", J. AM. SOC.NEPHROL, vol. 16, 2005, pages 3742 - 3747
BILEVICIUTE-LJUNGAR ET AL.: "evaluated the properties of K opioid receptor agonists for inflammatory diseases such as osteoarthritis and rheumatoid arthritis", RHEUMATOLOGY, vol. 45, 2006, pages 295 - 302
LEMBO: "evaluated the use of K opioid receptor agonists in gastrointestinal diseases", DIGES.DIS., vol. 24, 2006, pages 91 - 98
JOLIVALT ET AL.: "described the role of the K opioid receptor agonist acimadrine in rodent diabetic neuropathy", DIABETOLOGIA, vol. 49, no. 11, 2006, pages 2775 - 2785
See also references of EP 3656782A4
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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