Title:
PEPTIDE HAVING ANTIOXIDANT ACTIVITY AND COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2020/032622
Kind Code:
A1
Abstract:
The present invention provides a functional peptide having excellent antioxidant activity, the peptide having excellent biocompatibility and significantly better antioxidant activity than conventional GSHs in order to overcome the limitation of the weak antioxidant activity of existing peptides. The peptide of the present invention can promote antioxidant activity or effectively repair biological tissue or cell damage caused by reactive oxygen species generated due to oxidative stress. Therefore, the peptide having such antioxidant activity effectively acts on cell damage caused by oxidative stress, and can thus be used to prevent and repair cell damage.
Inventors:
LEE DAE HEE (KR)
UM HAET NIM (KR)
JEONG MOON KYUNG (KR)
HONG MI NA (KR)
PARK JUNG HEE (KR)
PARK YONG HAHK (KR)
HURH BYUNG SERK (KR)
UM HAET NIM (KR)
JEONG MOON KYUNG (KR)
HONG MI NA (KR)
PARK JUNG HEE (KR)
PARK YONG HAHK (KR)
HURH BYUNG SERK (KR)
Application Number:
PCT/KR2019/009972
Publication Date:
February 13, 2020
Filing Date:
August 08, 2019
Export Citation:
Assignee:
SEMPIO FOODS CO (KR)
International Classes:
C07K5/072; A23L33/18; A61K8/64; A61K38/00; A61Q19/00; C07K1/12; C07K5/093
Domestic Patent References:
| WO2011129462A2 | 2011-10-20 |
Foreign References:
| US8106020B2 | 2012-01-31 | |||
| KR20160116600A | 2016-10-10 |
Other References:
DATABASE PubChem 8 August 2005 (2005-08-08), Database accession no. 5489007
AMINO, Y. ET AL: "Structure-CaSR-activity relation of kokumi gamma-glutamyl peptides", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 64, no. 8, 2016, pages 1181 - 1189, XP055685276, ISSN: 0009-2363, DOI: 10.1248/cpb.c16-00293
MIRZAEI, M.: "Purification and identification of antioxidant and ACE-inhibitory peptide from Saccharomyces cerevisiae protein hydrolysate", JOURNAL OF FUNCTIONAL FOODS, vol. 19, 2015, pages 259 - 268, XP055685282, ISSN: 1756-4646, DOI: 10.1016/j.jff.2015.09.031
ALAM, M. N. ET AL., SAUDI PHARM. J., 2013
CURR. OPIN. NEUROL., vol. 9, no. 4, 1996, pages 260 - 264
MATES, JM ET AL., CLINICAL BIOCHEMISTRY, 1999
VRANKOVIC, J. ET AL., TURKISH JOURNAL OF BIOLOGY, 2012
LEE, J. M. ET AL., J. BIOCHEM. MOL. BIOL., 2004
BAIRD, L. ET AL., ARCH. TOXICOL., 2011
MERRIFIELD, J. AMER. CHEM. SOC., vol. 85, 1963, pages 2149 - 54
STEWART ET AL.: "Solid Phase Peptide Synthesis", 1984, PIERCE CHEM. CO., pages: 111
See also references of EP 3835307A4
AMINO, Y. ET AL: "Structure-CaSR-activity relation of kokumi gamma-glutamyl peptides", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 64, no. 8, 2016, pages 1181 - 1189, XP055685276, ISSN: 0009-2363, DOI: 10.1248/cpb.c16-00293
MIRZAEI, M.: "Purification and identification of antioxidant and ACE-inhibitory peptide from Saccharomyces cerevisiae protein hydrolysate", JOURNAL OF FUNCTIONAL FOODS, vol. 19, 2015, pages 259 - 268, XP055685282, ISSN: 1756-4646, DOI: 10.1016/j.jff.2015.09.031
ALAM, M. N. ET AL., SAUDI PHARM. J., 2013
CURR. OPIN. NEUROL., vol. 9, no. 4, 1996, pages 260 - 264
MATES, JM ET AL., CLINICAL BIOCHEMISTRY, 1999
VRANKOVIC, J. ET AL., TURKISH JOURNAL OF BIOLOGY, 2012
LEE, J. M. ET AL., J. BIOCHEM. MOL. BIOL., 2004
BAIRD, L. ET AL., ARCH. TOXICOL., 2011
MERRIFIELD, J. AMER. CHEM. SOC., vol. 85, 1963, pages 2149 - 54
STEWART ET AL.: "Solid Phase Peptide Synthesis", 1984, PIERCE CHEM. CO., pages: 111
See also references of EP 3835307A4
Attorney, Agent or Firm:
CHUNG HYUN PATENT & LAW FIRM (KR)
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