Title:
PEPTIDE HAVING WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/080578
Kind Code:
A1
Abstract:
The present invention relates to: a peptide exhibiting wound healing activity and anti-inflammatory activity; a fusion compound comprising same; and drugs, cosmetics, food, medical devices, etc. comprising same. The present inventors found that a Dualpep R1-9 peptide of SEQ ID NO: 10 and a variant thereof exhibit low cytotoxicity, significantly reduced a cell inflammatory response induced by lipopolysaccharides, and also exhibit wound healing efficacy.
Inventors:
PARK CHANHO (KR)
CHO SEONGMIN (KR)
CHO SEONGMIN (KR)
Application Number:
PCT/KR2022/016825
Publication Date:
May 11, 2023
Filing Date:
October 31, 2022
Export Citation:
Assignee:
REMEDI CO LTD (KR)
International Classes:
C07K7/08; A23L33/18; A61K8/64; A61K38/00; A61L15/32; A61L15/44; A61L27/22; A61L27/54; A61P17/00; A61Q19/00
Domestic Patent References:
| WO2014007547A1 | 2014-01-09 | |||
| WO2022255708A1 | 2022-12-08 |
Foreign References:
| KR100996047B1 | 2010-11-22 | |||
| US20170252396A1 | 2017-09-07 |
Other References:
ZHANG YUHAN, LIU WEIWEI, LI RONGHONG, GU JIAQI, WU PING, PENG CHAO, MA JINBIAO, WU LIGANG, YU YANG, HUANG YING: "Structural insights into the sequence-specific recognition of Piwi by Drosophila Papi", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, vol. 115, no. 13, 27 March 2018 (2018-03-27), pages 3374 - 3379, XP093063731, ISSN: 0027-8424, DOI: 10.1073/pnas.1717116115
YASHIRO RYU, MUROTA YUKIKO, NISHIDA KAZUMICHI M., YAMASHIRO HARUNA, FUJII KAEDE, OGAI ASUKA, YAMANAKA SOICHIRO, NEGISHI LUMI, SIOM: "Piwi Nuclear Localization and Its Regulatory Mechanism in Drosophila Ovarian Somatic Cells", CELL REPORTS, ELSEVIER INC, US, vol. 23, no. 12, 1 June 2018 (2018-06-01), US , pages 3647 - 3657, XP093063732, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2018.05.051
YASHIRO RYU, MUROTA YUKIKO, NISHIDA KAZUMICHI M., YAMASHIRO HARUNA, FUJII KAEDE, OGAI ASUKA, YAMANAKA SOICHIRO, NEGISHI LUMI, SIOM: "Piwi Nuclear Localization and Its Regulatory Mechanism in Drosophila Ovarian Somatic Cells", CELL REPORTS, ELSEVIER INC, US, vol. 23, no. 12, 1 June 2018 (2018-06-01), US , pages 3647 - 3657, XP093063732, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2018.05.051
Attorney, Agent or Firm:
KANG, Seong-Hea (KR)
Download PDF: