Title:
PEPTIDE FOR INDUCING REGENERATION OF TISSUE, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/199107
Kind Code:
A1
Abstract:
Provided is a peptide which can be used as an active ingredient for a composition that can be used for stimulating the migration of a PDGFRα-positive cell, a composition that can be used for mobilizing a bone marrow mesenchymal stem cell from the bone marrow to the peripheral blood, a composition that can be used for regenerating a tissue or a composition that can be used for stimulating the migration of a bone marrow-derived stromal cell.
Inventors:
NIHASHI YOICHIRO
KAWACHI TOMOYUKI
YAMATSU YUKIKO
FUMOTO MASATAKA
YAMAZAKI TAKEHIKO
KAWACHI TOMOYUKI
YAMATSU YUKIKO
FUMOTO MASATAKA
YAMAZAKI TAKEHIKO
Application Number:
PCT/JP2018/016654
Publication Date:
November 01, 2018
Filing Date:
April 24, 2018
Export Citation:
Assignee:
SHIONOGI & CO (JP)
GENOMIX CO LTD (JP)
GENOMIX CO LTD (JP)
International Classes:
C07K14/00; A61K38/16; A61P43/00
Domestic Patent References:
| WO2012147470A1 | 2012-11-01 | |||
| WO2014065347A1 | 2014-05-01 | |||
| WO2008053892A1 | 2008-05-08 | |||
| WO2007015546A1 | 2007-02-08 | |||
| WO2009133939A1 | 2009-11-05 | |||
| WO2009133943A1 | 2009-11-05 | |||
| WO2009133940A1 | 2009-11-05 | |||
| WO2012147470A1 | 2012-11-01 |
Foreign References:
| JP2005537253A | 2005-12-08 |
Other References:
KANEDA, YASUFUMI ET AL.: "Tissue restoration mechanism by bone marrow- derived stem cells", EXPERIMENTAL MEDICINE, vol. 31, no. 5, 1 January 2013 (2013-01-01), pages 655 - 661, XP009517389, ISSN: 0288-5514
KATSUHITO TAMAI: "Development on Regenerative-inducing Medicine Using Regeneration Mechanism for Damaged Body Tissues of Peripheral Circulation Mesenchymal Cells", BIO CLINICA, vol. 31, no. 10, 10 September 2016 (2016-09-10), pages 34 (1042) - 38 (1046), XP009517322, ISSN: 0919-8237
TAMAI, KATSUTO ET AL.: "PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, vol. 108, no. 16, 19 April 2011 (2011-04-19), pages 6609 - 6614, XP055044096
BUSTIN ET AL., MOL CELL BIOL, vol. 19, 1999, pages 5237 - 5246
HORI ET AL., J. BIOL. CHEM., vol. 270, 1995, pages 25752 - 25761
WANG ET AL., SCIENCE, vol. 285, 1999, pages 248 - 251
MULLER ET AL., EMBO J, vol. 20, 2001, pages 4337 - 4340
GERMANI ET AL., JLEUKOC BIOL., vol. 81, no. 1, January 2007 (2007-01-01), pages 59 - 66
PALUMBO ET AL., J. CELL BIOL., vol. 164, 2004, pages 441 - 449
MERENMIES ET AL., J. BIOL. CHEM., vol. 266, 1991, pages 16722 - 16729
WU Y ET AL., STEM CELLS, vol. 25, 2007, pages 2648 - 2659
TAMAI ET AL., PROC NATL ACAD SCI USA., 4 April 2011 (2011-04-04)
OGAWA ET AL., EMBO J, vol. 7, 1988, pages 1337 - 43
"Remington's Pharmaceutical Science", MARK PUBLISHING COMPANY
See also references of EP 3617222A4
KATSUHITO TAMAI: "Development on Regenerative-inducing Medicine Using Regeneration Mechanism for Damaged Body Tissues of Peripheral Circulation Mesenchymal Cells", BIO CLINICA, vol. 31, no. 10, 10 September 2016 (2016-09-10), pages 34 (1042) - 38 (1046), XP009517322, ISSN: 0919-8237
TAMAI, KATSUTO ET AL.: "PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, vol. 108, no. 16, 19 April 2011 (2011-04-19), pages 6609 - 6614, XP055044096
BUSTIN ET AL., MOL CELL BIOL, vol. 19, 1999, pages 5237 - 5246
HORI ET AL., J. BIOL. CHEM., vol. 270, 1995, pages 25752 - 25761
WANG ET AL., SCIENCE, vol. 285, 1999, pages 248 - 251
MULLER ET AL., EMBO J, vol. 20, 2001, pages 4337 - 4340
GERMANI ET AL., JLEUKOC BIOL., vol. 81, no. 1, January 2007 (2007-01-01), pages 59 - 66
PALUMBO ET AL., J. CELL BIOL., vol. 164, 2004, pages 441 - 449
MERENMIES ET AL., J. BIOL. CHEM., vol. 266, 1991, pages 16722 - 16729
WU Y ET AL., STEM CELLS, vol. 25, 2007, pages 2648 - 2659
TAMAI ET AL., PROC NATL ACAD SCI USA., 4 April 2011 (2011-04-04)
OGAWA ET AL., EMBO J, vol. 7, 1988, pages 1337 - 43
"Remington's Pharmaceutical Science", MARK PUBLISHING COMPANY
See also references of EP 3617222A4
Attorney, Agent or Firm:
HOSODA, Yoshinori (JP)
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