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Patent Searching and Data


Title:
PEPTIDE FOR INHIBITING BIOFILMS
Document Type and Number:
WIPO Patent Application WO/2018/186607
Kind Code:
A1
Abstract:
The present invention relates to: a composition for inhibiting biofilms, containing, as an active ingredient, a peptide derived from human β-defensin-3; and a method for inhibiting biofilms by using the composition. The peptide according to the present invention inhibits bacterial biofilms even when used alone and exhibits a remarkably increased biofilm inhibitory effect when used in combination with a conventional dental therapeutic agent, and has an effect of preventing a tooth discoloration side effect caused by a conventional dental therapeutic agent.

Inventors:
HAN SEUNG HYUN (KR)
KUM KEE-YEON (KR)
AHN KI BUM (KR)
PARK OK-JIN (KR)
CHUNG CHONG-PYOUNG (KR)
PARK YOON JEONG (KR)
LEE JUE-YEON (KR)
Application Number:
PCT/KR2018/003162
Publication Date:
October 11, 2018
Filing Date:
March 19, 2018
Export Citation:
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Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
NANO INTELLIGENT BIOMEDICAL ENG CORPORATION CO LTD (KR)
International Classes:
C07K7/08; A61K8/64; A61Q11/02
Foreign References:
KR20110098685A2011-09-01
KR101257228B12013-04-29
US20080274095A12008-11-06
Other References:
LIM, SANG-MIN ET AL.: "Antifungal Effects of Synthetic Human beta-defensin 3-C15 Peptide", RESTORATIVE DENTISTRY & ENDODONTICS, vol. 41, no. 2, 2016, pages 91 - 97, XP055559850
PEPPERNEY, ADAM ET AL.: "Antibacterial Peptides: Opportunities for the Prevention and Treatment of Dental Caries", PROBIOTICS & ANTIMICROBIAL PROTEINS, vol. 3, no. 2, June 2011 (2011-06-01), pages 68 - 96, XP055559853
YOO, YEON-JEE ET AL.: "Antifungal Effects of Synthetic Human Beta-defensin-3-C15 Peptide on Candida Albicans-infected Root Dentin", JOURNAL OF ENDODONTICS, vol. 43, no. 11, November 2017 (2017-11-01), pages 1857 - 1861, XP055635880
INT J DENT HYGIENE, vol. 12, 2014, pages 25 - 35
INT J DENT HYGIENE, vol. 13, 2015, pages 83 - 92
ACTA ODONTOLOGICA SCANDINAVICA, vol. 71, 2013, pages 1255 - 1260
INTERNATIONAL DENTAL JOURNAL, vol. 58, 2008, pages 81 - 85
See also references of EP 3608331A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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