Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PEPTIDE AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2021/002408
Kind Code:
A1
Abstract:
The present invention provides a peptide having a fluoroalkyl group as a side chain. The present invention is a method for manufacturing a fluoroalkyl-group-containing peptide in which a compound represented by general formula (6-2) or (6-4) (* indicates that the absolute configuration of an asymmetric carbon atom indicated by * is S or R; Rf is a C1-30 alkyl group (if the C1-30 alkyl group is a C2-30 alkyl group, there may be 1 to 5 ether-bonding oxygen atoms between the carbon atoms) substituted by at least two fluorine atoms and which may further be substituted by halogen atoms other than fluorine atoms; and R2 is a protection group of an amino group) is condensed with a fluorine-containing amino acid in which the carboxy group is protected, an amino acid in which the carboxy group is protected, a fluorine-containing peptide in which the C-terminus is protected, or a peptide in which the C-terminus is protected.

Inventors:
OKAZOE TAKASHI (JP)
ISHIBASHI YUICHIRO (JP)
SANDO SHINSUKE (JP)
MORIMOTO JUMPEI (JP)
AIKAWA KOHSUKE (JP)
MIKAMI TOSHIKI (JP)
ONO TAKAHIRO (JP)
Application Number:
JP2020/025912
Publication Date:
January 07, 2021
Filing Date:
July 01, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
AGC INC (JP)
UNIV TOKYO (JP)
International Classes:
C07C231/12; C07C237/12; C07C269/06; C07C271/22; C07K1/06; C07K1/10; C07K5/00; C07K5/08; C07K5/083
Attorney, Agent or Firm:
T.S. PARTNERS et al. (JP)
Download PDF: