Title:
PEPTIDE PAC1 ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/2018/222991
Kind Code:
A3
Abstract:
Novel peptides that bind to human PAC1 are provided. These peptides that are antagonists of PAC1 are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine, such as acute migraine.
Inventors:
CHEN IRWIN (US)
CHONG SU (US)
HARRINGTON ESSA HU (US)
HONG FANG-TSAO (US)
LONG JASON C (US)
MIRANDA LESLIE P (US)
CHONG SU (US)
HARRINGTON ESSA HU (US)
HONG FANG-TSAO (US)
LONG JASON C (US)
MIRANDA LESLIE P (US)
Application Number:
PCT/US2018/035597
Publication Date:
January 31, 2019
Filing Date:
June 01, 2018
Export Citation:
Assignee:
AMGEN INC (US)
International Classes:
A61K38/00
Domestic Patent References:
| WO2009033489A2 | 2009-03-19 |
Foreign References:
| US6462016B1 | 2002-10-08 | |||
| US20020182729A1 | 2002-12-05 | |||
| CN101125881A | 2008-02-20 |
Other References:
VOLLESEN ANNE LUISE HAULUND ET AL: "PACAP38: Emerging Drug Target in Migraine and Cluster Headache", HEADACHE, vol. 57, no. Suppl. S2, Sp. Iss. SI, May 2017 (2017-05-01), pages 56 - 63, XP002784460
Attorney, Agent or Firm:
MEKHOVICH, Olga (US)
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