Title:
PEPTIDE FOR PRODUCTION OF KILLED VACCINE AND KILLED VACCINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2018/044018
Kind Code:
A1
Abstract:
The present invention relates to a peptide for the production of an inactivated vaccine and an inactivated vaccine using the same and, more particularly, to a mastoparan peptide for the production of an inactivated vaccine and a method for producing an inactivated vaccine using the same. The inactivated vaccine prepared by treating the mastoparan peptide according to the present invention is safe as compared to an inactivated vaccine prepared by chemical treatment of formalin, etc. and also has an immunity inducing ability equal to or superior to that of a live vaccine.
Inventors:
BANG WOO YOUNG (KR)
BAE CHANG-HWAN (KR)
YEO JOO-HONG (KR)
HUR JIN (KR)
MOON SEONG CHEOL (KR)
JUNG HO KYOUNG (KR)
BAE CHANG-HWAN (KR)
YEO JOO-HONG (KR)
HUR JIN (KR)
MOON SEONG CHEOL (KR)
JUNG HO KYOUNG (KR)
Application Number:
PCT/KR2017/009390
Publication Date:
March 08, 2018
Filing Date:
August 28, 2017
Export Citation:
Assignee:
NAT INSTITUTE OF BIOLOGICAL RESOURCES (KR)
NAT UNIV CHONBUK IND COOP FOUND (KR)
KOMIPHARM INT CO LTD (KR)
NAT UNIV CHONBUK IND COOP FOUND (KR)
KOMIPHARM INT CO LTD (KR)
International Classes:
C07K7/08; A61K39/00; A61K39/02
Foreign References:
| US20120201782A1 | 2012-08-09 |
Other References:
KIM, Y. ET AL.: "MP-V1 from the Venom of Social Wasp Vespula Vulgaris Is a De Novo Type of Mastoparan that Displays Superior Antimicrobial Activities", MOLECULES, vol. 21, no. 512, 19 April 2016 (2016-04-19), pages 1 - 10, XP055470340
KING, T. P. ET AL.: "Inflammatory Role of Two Venom Components of Yellow Jackets (Vespula Vulgaris): a Mast Cell Degranulating Peptide Mastoparan and Phospholipase Al", INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, vol. 131, 2003, pages 25 - 32
DATABASE Protein [O] 12 April 2017 (2017-04-12), XP055470357, Database accession no. P0C1Q8.1
MORENO, M. ET AL.: "Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan", TOXINS, vol. 7, 2015, pages 1126 - 1150, XP05547037
YANG, M. J. ET AL.: "Enhancing Antimicrobial Activity of Mastoparan-B by Amino Acid Substitutions", JOURNAL OF ASIA-PACIFIC ENTOMOLOGY, vol. 16, 2013, pages 349 - 355, XP028741949
JI, JAE HO: "Finding a new killed vaccine production method from the poison of vespula vulgaris", DAILY GRID, 9 September 2016 (2016-09-09), Retrieved from the Internet
KING, T. P. ET AL.: "Inflammatory Role of Two Venom Components of Yellow Jackets (Vespula Vulgaris): a Mast Cell Degranulating Peptide Mastoparan and Phospholipase Al", INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, vol. 131, 2003, pages 25 - 32
DATABASE Protein [O] 12 April 2017 (2017-04-12), XP055470357, Database accession no. P0C1Q8.1
MORENO, M. ET AL.: "Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan", TOXINS, vol. 7, 2015, pages 1126 - 1150, XP05547037
YANG, M. J. ET AL.: "Enhancing Antimicrobial Activity of Mastoparan-B by Amino Acid Substitutions", JOURNAL OF ASIA-PACIFIC ENTOMOLOGY, vol. 16, 2013, pages 349 - 355, XP028741949
JI, JAE HO: "Finding a new killed vaccine production method from the poison of vespula vulgaris", DAILY GRID, 9 September 2016 (2016-09-09), Retrieved from the Internet
Attorney, Agent or Firm:
AHN, Chang Woo (KR)
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