Title:
PEPTIDE TARGETING MYCOBACTERIUM
TUBERCULOSIS TOXIN-ANTITOXIN SYSTEM AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/027224
Kind Code:
A2
Abstract:
The present invention relates to a peptide targeting a toxin-antitoxin system of Mycobacterium
tuberculosis and a use thereof. Specifically, the antibiotic peptide of the present invention inhibits the formation of a toxin-antitoxin complex of Mycobacterium
tuberculosis without affecting an active site of the toxin, thereby inducing the death of Mycobacterium
tuberculosis by means of a separated toxin. Therefore, the antibiotic peptide can be usefully used as an antibiotic composition against Mycobacterium
tuberculosis.
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Inventors:
LEE BONG-JIN (KR)
KANG SUNG-MIN (KR)
KIM DO-HEE (KR)
KANG SUNG-MIN (KR)
KIM DO-HEE (KR)
Application Number:
PCT/KR2018/008680
Publication Date:
February 07, 2019
Filing Date:
July 31, 2018
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
International Classes:
C07K7/08; A61K38/00
Attorney, Agent or Firm:
LEE, Won Hee (KR)
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