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Title:
PEPTIDE-UREA DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/030509
Kind Code:
A1
Abstract:
A peptide-urea derivative, a pharmaceutical composition containing same and an application thereof are provided, the derivative being as shown in formula I. The derivative can be used for preoperative imaging diagnosis and grading of PSMA-positive prostate cancer, and can also be used for the treatment of various types and stages of prostate cancer, achieving the integration of diagnosis and treatment, and having broad application prospects.

Inventors:
YU HAIHUA (CN)
WANG ERIC YANJUN (CN)
WANG KEVIN YU (CN)
Application Number:
PCT/CN2022/116897
Publication Date:
March 09, 2023
Filing Date:
September 02, 2022
Export Citation:
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Assignee:
BIVISION PHARMACEUTICALS INC (CN)
International Classes:
C07F13/00; A61K51/04; A61K103/00; A61K103/30; A61K103/40; A61P35/00; C07K5/037
Domestic Patent References:
WO2022101352A12022-05-19
WO2021013978A12021-01-28
Foreign References:
CN111253465A2020-06-09
CN112074526A2020-12-11
CN109641924A2019-04-16
CN112770785A2021-05-07
CN105636924A2016-06-01
CN111491668A2020-08-04
CN110740757A2020-01-31
CN111630059A2020-09-04
CN202111031423A2021-09-03
Other References:
MEDER ET AL., BIOCONJUGATE CHEM, vol. 23, 2012, pages 688 - 697
RAYMOND C ROWE: "Pharmacopoeia of the People's Republic of China", 2009, HANDBOOK OF PHARMACEUTICAL
JIANGSU HUAJING: "Molecular Imaging", DRUG RESEARCH INSTITUTE CO.
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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