PEPTIDE VACCINE FOR INFLUENZA VIRUS

WIPO Patent Application WO2008049974

A8

The invention provides peptide epitopes for use in the prevention and/or treatment of influenza or for the development of such treatment or vaccine against influenza. The invention also relates to a method for evaluating the potential of a chemical entity, such as an antibody, to bind to a peptide epitope derived from the divalent sialoside binding site of hemagglutinin protein of influenza virus, and to conjugates containing one or more such peptide epitopes. The peptide epitopes of the invention are cyclic peptides comprising a 7-mer peptide derived from H1, H3 or H5 hemagglutinin of influenza virus. The 7-mer peptide has a sequence corresponding to the loop sequence at positions 220-226 of X31-hemagglutinin.

WO/1996/004298	PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
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NATUNEN JARI (FI)
HILTUNEN JUKKA (FI)
NIEMELAE RITVA (FI)
HELIN JARI (FI)
AITIO OLLI (FI)

PCT/FI2007/050577

June 19, 2008

October 26, 2007

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GLYKOS FINLAND OY (FI)
NATUNEN JARI (FI)
HILTUNEN JUKKA (FI)
NIEMELAE RITVA (FI)
HELIN JARI (FI)
AITIO OLLI (FI)

C07K7/06; A61K38/08; C07K14/11; A61K31/7028; A61P31/16; C07H15/00

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