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Title:
PEPTIDE WITH ANTI-AGING EFFECT AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/157485
Kind Code:
A1
Abstract:
The present invention addresses the problem of discovering a short chain peptide with an anti-aging effect and providing a novel anti-aging agent containing said peptide as an active ingredient. It was found that peptides, which have at least one kind of effect selected from a group consisting of fibroblast proliferation-promoting effects, hyaluronic acid production-promoting effects and collagen gel shrinkage effects and are obtained from an amino acid sequence represented by ELKLIFLHRLKRLRKRLKRK (Sequence No. 1), a partial sequence thereof, or a derivative or salt thereof are useful as active ingredients for anti-aging agents.

Inventors:
NAKAGAMI HIRONORI (JP)
MORISHITA RYUICHI (JP)
TOMIOKA HIDEKI (JP)
TENMA AKIKO (JP)
Application Number:
PCT/JP2014/058786
Publication Date:
October 02, 2014
Filing Date:
March 27, 2014
Export Citation:
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Assignee:
UNIV OSAKA (JP)
International Classes:
C07K7/08; A23L1/305; A61K8/64; A61K38/00; A61P17/00; A61P43/00; A61Q19/08; C07K7/06; C07K5/083; C07K5/11
Domestic Patent References:
WO2010061915A12010-06-03
WO2010137594A12010-12-02
WO2008096814A12008-08-14
WO2005090564A12005-09-29
WO2010061915A12010-06-03
WO2010101237A12010-09-10
WO2010137594A12010-12-02
Foreign References:
JP2013129648A2013-07-04
JP2011042613A2011-03-03
JP2012014583A2012-01-19
Other References:
AKIKO TENMA ET AL.: "Development of functional peptides with anti-aging effects and antimicrobial activity", FRAGRANCE JOURNAL, vol. 40, no. 6, 2012, pages 59 - 63, XP009190893
J. CELL. MOL. MED., vol. 13, 2008, pages 535 - 46
J. CELL. MOL. MED., vol. 16, no. 7, 2012, pages 1629 - 1639
"Solid Phase Peptide Synthesis", 1984, PIERCE
"Fmoc solid synthesis: a practical approach", 2000, OXFORD UNIVERSITY PRESS
"The Fifth Series of Experimental Chemistry (Jikken Kagaku Koza", vol. 16
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
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